Počet záznamů: 1

Carbon Nanomaterials for Bioimaging, Bioanalysis, and Therapy

SYSNO ASEP	0521416
Druh ASEP	M - Kapitola v monografii
Zařazení RIV	C - Kapitola v knize
Název	Using Polymers to Enhance the Carbon Nanomaterial Biointerface
Tvůrce(i)	Pramanik, Goutam (UOCHB-X)_ORCID Neburková, Jitka (UOCHB-X)_{RID, ORCID} Vaněk, Václav (UOCHB-X)_{RID, ORCID} Jani, Mona (UOCHB-X) Kindermann, Marek (UOCHB-X) Cígler, Petr (UOCHB-X)_{RID, ORCID}
Zdroj.dok.	Carbon Nanomaterials for Bioimaging, Bioanalysis, and Therapy. - Hoboken : Wiley, 2019 / Hui Y. Y. ; Chang H.-C. ; Dong H. ; Zhang X. - ISBN 978-1-119-37345-2
Rozsah stran	s. 15-42
Poč.str.	28 s.
Poč.str.knihy	376
Forma vydání	Tištěná - P
Jazyk dok.	eng - angličtina
Země vyd.	US - Spojené státy americké
Klíč. slova	biomedical applications ; carbon nanomaterials ; covalent modification ; DLVO theory ; noncovalent coating ; nucleic acids ; polymer functionalization ; stimuli‐responsive polymers
Vědní obor RIV	CD - Makromolekulární chemie
Obor OECD	Nano-materials (production and properties)
CEP	GA18-17071S GA ČR - Grantová agentura ČR
	EF16_019/0000729 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy
Institucionální podpora	UOCHB-X - RVO:61388963
DOI	10.1002/9781119373476.ch2
Anotace	This chapter focuses on functionalization of carbon nanomaterials (CNMs) with polymers for biomedical applications. A classical theoretical approach based on Derjaguin‐Landau‐Verwey‐Overbeek (DLVO) theory is commonly used to predict the stability of a colloidal system. CNMs can be functionalized with polymers via two types of approaches: noncovalent coating and covalent modification. The physicochemical properties of CNMs are determined by their intrinsic nanostructure. The chapter discusses the effect of polymer functionalization on the spectral properties of various CNMs. Stimuli‐responsive polymers respond to their environment by changing their physical and/or chemical properties. Among stimuli‐responsive polymers, thermoresponsive polymers have been exploited most abundantly to modify carbon nanoparticles. The development of nonviral, nonimmunogenic, and biocompatible vectors for efficient intracellular transfection of nucleic acids (NAs) is one of the challenges facing future gene therapy approaches. The surface of the CNMs can be functionalized by covalent or noncovalent attachment of macromolecular layers to create reliable nonviral gene delivery vectors.
Pracoviště	Ústav organické chemie a biochemie
Kontakt	asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434
Rok sběru	2020

Počet záznamů: 1