Počet záznamů: 1
Design of the reversible biphasic arrangement in the microfluidic chip reactor for asymmetric hydrogenation reactions.
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SYSNO ASEP 0518838 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Design of the reversible biphasic arrangement in the microfluidic chip reactor for asymmetric hydrogenation reactions. Tvůrce(i) Klusoň, Petr (UCHP-M) RID, ORCID, SAI
Stavárek, Petr (UCHP-M) RID, ORCID, SAI
Pěnkavová, Věra (UCHP-M) RID, ORCID, SAI
Vychodilová, Hana (UCHP-M) RID, SAI
Hejda, Stanislav (UCHP-M) RID, ORCID, SAI
Bendová, Magdalena (UCHP-M) RID, ORCID, SAI
Došek, M. (CZ)Zdroj.dok. Chemical Engineering Research and Design. - : Elsevier - ISSN 0263-8762
Roč. 153, January (2020), s. 537-546Poč.str. 10 s. Jazyk dok. eng - angličtina Země vyd. NL - Nizozemsko Klíč. slova reversible biphasic system ; microfluidic chip reactor ; catalyst recovery Vědní obor RIV CI - Průmyslová chemie a chemické inženýrství Obor OECD Chemical process engineering CEP GA15-04790S GA ČR - Grantová agentura ČR Způsob publikování Open access Institucionální podpora UCHP-M - RVO:67985858 UT WOS 000510526400045 EID SCOPUS 85075591042 DOI 10.1016/j.cherd.2019.11.023 Anotace Design of the reversible biphasic system for a practical use in asymmetric hydrogenation performed in a microfluidic chip reactor is reported. Methylacetoacetate (MAA) was transformed to (R)-methylhydroxybutyrate over optically pure (R)-Ru-BINAP as a model reaction. The study was an iteration towards the design, description and optimization of the temperature driven reversible biphasic system in the mixed [NR,222][Tf2N]/methanol/water phase by varying the parameter of the structure of the ionic molecule, starting from [NH4][Tf2N] up to [N14,222][Tf2N]. At temperatures, and other conditions providing high conversions and optical yields, the reaction mixture was monophasic. At lower temperatures, the mixture became biphasic for ionic liquids with long alkyl chains (namely [N14,222][Tf2N]) due to their strong non-polar character. The formed ionic liquid phase accommodated the chiral Ru complex, the water/methanol phase the reaction products. After the reaction, when the mixture was cooled, over 90% of the catalytic complex was kept in the ionic liquid phase. Viscosity and density data were also discussed. It seems the reversible biphasic system offers a way to facilitate the separation of the chiral Ru-complex from the reaction mixture. Due to high sensitivity of the complex to handling conditions, its reuse still requires further optimization. Pracoviště Ústav chemických procesů Kontakt Eva Jirsová, jirsova@icpf.cas.cz, Tel.: 220 390 227 Rok sběru 2021 Elektronická adresa https://www.sciencedirect.com/science/article/pii/S0263876219305490?via%3Dihub
Počet záznamů: 1