Počet záznamů: 1
Evaluation of silica from different vendors as the solid support of anion-exchange chiral stationary phases by means of preferential sorption and liquid chromatography.
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SYSNO ASEP 0511718 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Evaluation of silica from different vendors as the solid support of anion-exchange chiral stationary phases by means of preferential sorption and liquid chromatography. Tvůrce(i) Kohout, P. (CZ)
Hovorka, Š. (CZ)
Herciková, J. (CZ)
Wilk, M. (CZ)
Sysel, P. (CZ)
Izák, Pavel (UCHP-M) RID, ORCID, SAI
Bartůněk, V. (CZ)
von Baeckmann, C. (AT)
Pícha, Jan (UOCHB-X) RID, ORCID
Frühauf, P. (AT)Zdroj.dok. Journal of Separation Science. - : Wiley - ISSN 1615-9306
Roč. 42, č. 24 (2019), s. 3653-3661Poč.str. 9 s. Jazyk dok. eng - angličtina Země vyd. DE - Německo Klíč. slova chiral anion exchanger ; preferential sorption ; liquid chromatography Vědní obor RIV CI - Průmyslová chemie a chemické inženýrství Obor OECD Chemical process engineering Vědní obor RIV – spolupráce Ústav organické chemie a biochemie - Analytická chemie, separace CEP GA17-00089S GA ČR - Grantová agentura ČR Způsob publikování Omezený přístup Institucionální podpora UCHP-M - RVO:67985858 ; UOCHB-X - RVO:61388963 UT WOS 000493821900001 EID SCOPUS 85074777197 DOI 10.1002/jssc.201900731 Anotace Chromatographic performance of a chiral stationary phase is significantly influenced by the employed solid support. Properties of the most commonly used support, silica particles, such as size and size distribution, and pore size are of utmost importance for both superficially porous particles and fully porous particles. In this work, we have focused on evaluation of fully porous particles from three different vendors as solid supports for a brush-type chiral stationary phase based on 9-O-tert-butylcarbamoyl quinidine. We have prepared corresponding stationary phases under identical experimental conditions and determined the parameters of the modified silica by physisorption measurements and scanning electron microscopy. Enantiorecognition properties of the chiral stationary phases have been studied using preferential sorption experiments. The same material was slurry-packed into chromatographic columns and the chromatographic properties have been evaluated in liquid chromatography. We show that preferential sorption can provide valuable information about the influence of the pore size and total pore volume on the interaction of analytes of different size with the chirally-modified silica surface. The data can be used to understand differences observed in chromatographic evaluation of the chiral stationary phases. The combination of preferential sorption and liquid chromatography separation can provide detailed information on new chiral stationary phases. Pracoviště Ústav chemických procesů Kontakt Eva Jirsová, jirsova@icpf.cas.cz, Tel.: 220 390 227 Rok sběru 2020 Elektronická adresa http://hdl.handle.net/11104/0303439
Počet záznamů: 1