Počet záznamů: 1
The distribution of epigenetic histone marks differs between the X and Y chromosomes in Silene latifolia
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SYSNO ASEP 0509308 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název The distribution of epigenetic histone marks differs between the X and Y chromosomes in Silene latifolia Tvůrce(i) Bačovský, Václav (BFU-R) ORCID
Houben, A. (DE)
Kumke, K. (DE)
Hobza, Roman (BFU-R) RID, ORCIDCelkový počet autorů 4 Zdroj.dok. Planta. - : Springer - ISSN 0032-0935
Roč. 250, č. 2 (2019), s. 487-494Poč.str. 8 s. Forma vydání Tištěná - P Jazyk dok. eng - angličtina Země vyd. DE - Německo Klíč. slova plant chromosomes ; sex-chromosomes ; chromatin-structure Vědní obor RIV EF - Botanika Obor OECD Plant sciences, botany CEP GA18-06147S GA ČR - Grantová agentura ČR GA16-08698S GA ČR - Grantová agentura ČR Způsob publikování Omezený přístup Institucionální podpora BFU-R - RVO:68081707 UT WOS 000474429800007 DOI 10.1007/s00425-019-03182-7 Anotace Main conclusionContrasting patterns of histone modifications between the X and Y chromosome in Silene latifolia show euchromatic histone mark depletion on the Y chromosome and indicate hyperactivation of one X chromosome in females.AbstractSilene latifolia (white campion) is a dioecious plant with heteromorphic sex chromosomes (24, XX in females and 24, XY in males), and a genetically degenerated Y chromosome that is 1.4 times larger than the X chromosome. Although the two sex chromosomes differ in their DNA content, information about epigenetic histone marks and evidence of their function are scarce. We performed immunolabeling experiments using antibodies specific for active and suppressive histone modifications as well as pericentromere-specific histone modifications. We show that the Y chromosome is partially depleted of histone modifications important for transcriptionally active chromatin, and carries these marks only in the pseudo-autosomal region, but that it is not enriched for suppressive and pericentromere histone marks. We also show that two of the active marks are specifically enriched in one of the X chromosomes in females and in the X chromosome in males. Our data support recent findings that genetic imprinting mediates dosage compensation of sex chromosomes in S. latifolia. Pracoviště Biofyzikální ústav Kontakt Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Rok sběru 2020 Elektronická adresa https://link.springer.com/article/10.1007%2Fs00425-019-03182-7
Počet záznamů: 1