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Identification of short-chain poly-3-hydroxybutyrates in Saiga horn extracts using LC-MS/MS
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SYSNO ASEP 0504500 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Identification of short-chain poly-3-hydroxybutyrates in Saiga horn extracts using LC-MS/MS Tvůrce(i) Pataridis, Statis (FGU-C)
Romanov, O. (RU)
Mikšík, Ivan (FGU-C) RID, ORCID, SAIZdroj.dok. Journal of Separation Science. - : Wiley - ISSN 1615-9306
Roč. 42, č. 4 (2019), s. 797-808Poč.str. 12 s. Jazyk dok. eng - angličtina Země vyd. DE - Německo Klíč. slova liquid chromatography ; polyhydroxybutyrates ; Saiga horn ; tandem mass spectrometry ; traditional Chinese medicine Vědní obor RIV CB - Analytická chemie, separace Obor OECD Analytical chemistry CEP GA17-10832S GA ČR - Grantová agentura ČR Způsob publikování Omezený přístup Institucionální podpora FGU-C - RVO:67985823 UT WOS 000459327100002 EID SCOPUS 85060336752 DOI 10.1002/jssc.201800910 Anotace Saiga horn extracts were analyzed with the goal of obtaining new information about compounds present in it. The purpose of this study is to find synthetic alternatives to Saiga horn extract, which is used in traditional Chinese medicine, by identifying potentially biologically active compounds in the extracts. Using high‐performance liquid chromatography coupled with high‐resolution mass spectrometry, we have been able to identify a series of short‐chain polyhydroxybutyrates in alcoholic extracts of Saiga horn. Optimized high‐performance liquid chromatography coupled with tandem mass spectrometry methods for analysis of short‐chain poly‐3‐hydroxybutyrates were developed and subsequently applied to investigate Saiga horn extract for the presence of these compounds, which might explain its biological actions, particularly for its antipyretic and procoagulant properties. Pracoviště Fyziologický ústav Kontakt Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Rok sběru 2020 Elektronická adresa https://doi.org/10.1002/jssc.201800910
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