Počet záznamů: 1
Beta-glucans and cholesterol
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SYSNO ASEP 0488761 Druh ASEP J - Článek v odborném periodiku Zařazení RIV Záznam nebyl označen do RIV Poddruh J Článek ve WOS Název Beta-glucans and cholesterol Tvůrce(i) Šíma, Petr (MBU-M)
Vannucci, Luca (MBU-M) RID, ORCID
Větvička, V. (US)Zdroj.dok. International Journal of Molecular Medicine. - : Spandidos Publications - ISSN 1107-3756
Roč. 41, č. 4 (2018), s. 1799-1808Poč.str. 10 s. Jazyk dok. eng - angličtina Země vyd. GR - Řecko Klíč. slova cholesterol ; beta-glucans ; diet Vědní obor RIV EE - Mikrobiologie, virologie Obor OECD Microbiology Způsob publikování Open access Institucionální podpora MBU-M - RVO:61388971 UT WOS 000427160600001 EID SCOPUS 85041557156 DOI 10.3892/ijmm.2018.3411 Anotace Hypercholesterolemia is one of primary risk factors of cardiovascular disease, together with metabolic syndrome, hypertension and diabetes. Although progress has been made, the search for novel methods of preventing and treating dyslipidemia is ongoing and current therapies for cardiovascular disease induce various side effects. -glucans are linear unbranched polysaccharides found in various natural sources, such as mushrooms. Due to their structure they are able to interact with innate immunity receptors, however they also act as dietary fibers in the digestive tract. As there are two forms of -glucans, insoluble and soluble forms, they are able to interact with lipids and biliary salts in the bowel and consequently reduce cholesterol levels. Therefore, they may be developed as a suitable therapeutic option to treat patients with dyslipidemia, as they are natural molecules that do not induce any significant side effects. The current review discusses the evidence supporting the effects of -glucans on cholesterol levels.
Pracoviště Mikrobiologický ústav Kontakt Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Rok sběru 2021 Elektronická adresa https://www.spandidos-publications.com/10.3892/ijmm.2018.3411
Počet záznamů: 1