Počet záznamů: 1
Static high-gradient magnetic fields affect the functionality of monocytic cells
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SYSNO ASEP 0486097 Zařazení RIV O - Ostatní Název Static high-gradient magnetic fields affect the functionality of monocytic cells Tvůrce(i) Syrovets, T. (DE)
Schmidt, Z. (DE)
Buechele, B. (DE)
Zablotskyy, Vitaliy A. (FZU-D) RID
Dejneka, Alexandr (FZU-D) RID, ORCID
Dempsey, N. (FR)
Simmet, T. (DE)Celkový počet autorů 7 Zdroj.dok. FASEB JOURNAL, 2. - BETHESDA : FEDERATION AMER. SOC. EXP. BIOL., 2014 - ISSN 0892-6638
Roč. 28, č. 1 (2014), s. 1-2Poč.str. 2 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova static high-gradient ; magnetic fields ; affect the functionality ; monocytic cells Vědní obor RIV BM - Fyzika pevných látek a magnetismus Obor OECD Condensed matter physics (including formerly solid state physics, supercond.) Institucionální podpora FZU-D - RVO:68378271 UT WOS 000346651000058 Anotace Magnetic fields, different to electric fields, can intrude into deeper layers of tissue, where they could modulate biochemical processes. In this context, we explored the cellular effects of specifically designed high-performance micro-magnet arrays which, in contrast to conventional magnets, generate high-gradient magnetic fields not encountered in the environment. Exposure of monocytic cells to high-gradient magnetic fields of various strength generated by micro-magnet arrays induced cell swelling followed by accumulation of reactive oxygen species (ROS), and inhibition of cell proliferation. High levels of ROS may damage cellular structures and induce apoptosis. Consistently, prolonged exposure of cells to high-gradient magnetic fields induced time-dependent translocation of phosphatidylserine to the outer leaflet of the membrane. Pracoviště Fyzikální ústav Kontakt Kristina Potocká, potocka@fzu.cz, Tel.: 220 318 579 Rok sběru 2018
Počet záznamů: 1