Počet záznamů: 1
Parallel genome reduction in symbionts descended from closely related free-living bacteria
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SYSNO ASEP 0483952 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Parallel genome reduction in symbionts descended from closely related free-living bacteria Tvůrce(i) Boscaro, V. (CA)
Kolísko, Martin (BC-A) ORCID
Felletti, M. (DE)
Vannini, C. (IT)
Lynn, D. H. (CA)
Keeling, P.J. (CA)Celkový počet autorů 6 Zdroj.dok. Nature Ecology & Evolution - ISSN 2397-334X
Roč. 1, č. 8 (2017), s. 1160-1167Poč.str. 8 s. Forma vydání Tištěná - P Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova polynucleobacter-necessarius ; phylogenetic analysis ; maximum-likelihood ; evolution ; replacement ; model ; endosymbionts ; acceleration ; perspectives Vědní obor RIV EB - Genetika a molekulární biologie Obor OECD Biochemistry and molecular biology Institucionální podpora BC-A - RVO:60077344 UT WOS 000417188600023 EID SCOPUS 85030624183 DOI 10.1038/s41559-017-0237-0 Anotace Endosymbiosis plays an important role in ecology and evolution, but fundamental aspects of the origin of intracellular symbionts remain unclear. The extreme age of many symbiotic relationships, lack of data on free-living ancestors and uniqueness of each event hinder investigations. Here, we describe multiple strains of the bacterium Polynucleobacter that evolved independently and under similar conditions from closely related, free-living ancestors to become obligate endosymbionts of closely related ciliate hosts. As these genomes reduced in parallel from similar starting states, they provide unique glimpses into the mechanisms underlying genome reduction in symbionts. We found that gene loss is contingently lineage-specific, with no evidence for ordered streamlining. However, some genes in otherwise disrupted pathways are retained, possibly reflecting cryptic genetic network complexity. We also measured substitution rates between many endosymbiotic and free-living pairs for hundreds of genes, which showed that genetic drift, and not mutation pressure, is the main non-selective factor driving molecular evolution in endosymbionts. Pracoviště Biologické centrum (od r. 2006) Kontakt Dana Hypšová, eje@eje.cz, Tel.: 387 775 214 Rok sběru 2018
Počet záznamů: 1