Počet záznamů: 1

Nanoparticles with Embedded Porphyrin Photosensitizers for Photooxidation Reactions and Continuous Oxygen Sensing

SYSNO ASEP	0480025
Druh ASEP	J - Článek v odborném periodiku
Zařazení RIV	J - Článek v odborném periodiku
Poddruh J	Článek ve WOS
Název	Nanoparticles with Embedded Porphyrin Photosensitizers for Photooxidation Reactions and Continuous Oxygen Sensing
Tvůrce(i)	Kubát, Pavel (UFCH-W)_{RID, ORCID, SAI} Henke, P. (CZ) Berzediová, V. (CZ) Štěpánek, M. (CZ) Lang, Kamil (UACH-T)_{SAI, RID, ORCID} Mosinger, Jiří (UACH-T)_{RID, ORCID, SAI}
Zdroj.dok.	ACS Applied Materials and Interfaces. - : American Chemical Society - ISSN 1944-8244 Roč. 9, č. 41 (2017), s. 36229-36238
Poč.str.	10 s.
Jazyk dok.	eng - angličtina
Země vyd.	US - Spojené státy americké
Klíč. slova	photooxidation ; polystyrene nanoparticles ; porphyrins
Vědní obor RIV	CF - Fyzikální chemie a teoretická chemie
Obor OECD	Physical chemistry
Vědní obor RIV – spolupráce	Ústav anorganické chemie - Anorganická chemie
CEP	GA16-15020S GA ČR - Grantová agentura ČR
Institucionální podpora	UFCH-W - RVO:61388955 ; UACH-T - RVO:61388980
UT WOS	000413503700075
EID SCOPUS	85031725427
DOI	10.1021/acsami.7b12009
Anotace	We report the synthesis and characterization of sulfonated polystyrene nanoparticles (average diameter 30 +/- 14 nm) with encapsulated 5,10,15,20-tetraphenylporphyrin or ionically entangled tetracationic 5,10,15,20-tetralcis(N-methylpyridinium-4-yl)-porphyrin, their photooxidation properties, and the application of singlet oxygen-sensitized delayed fluorescence (SODF) in oxygen sensing. Both types of nanoparticles effectively photogenerated singlet oxygen, O-2((1)Delta(g)). The O-2((1)Delta(g)) phosphorescence, transient absorption of the porphyrin triplet states, and SODF signals were monitored using time-resolved spectroscopic techniques. The SODF intensity depended on the concentration of the porphyrin photosensitizer and dissolved oxygen and on the temperature. After an initial period (a few microseconds), the kinetics of the SODF process can be approximated as a monoexponential function, and the apparent SODF lifetimes can be correlated with the oxygen concentration. The oxygen sensing based on SODF allowed measurement of the dissolved oxygen in aqueous media in the broad range of oxygen concentrations (0.2-38 mg L-1). The ability of both types of nanoparticles to photooxidize external substrates was predicted by the SODF measurements and proven by chemical tests. The relative photooxidation efficacy was highest at a low porphyrin concentration, as indicated by the highest fluorescence quantum yield (Phi(F)), and it corresponds with negligible inner filter and self-quenching effects. The photooxidation abilities were sensitive to the influence of temperature on the diffusion and solubility of oxygen in both polystyrene and water media and to the rate constant of the O-2((1)Delta(g)) reaction with a substrate. Due to their efficient photogeneration of cytotoxic O-2((1)Delta(g)) at physiological temperatures and their oxygen sensing via SODF, both types of nanoparticles are promising candidates for biomedical applications.
Pracoviště	Ústav fyzikální chemie J.Heyrovského
Kontakt	Michaela Knapová, michaela.knapova@jh-inst.cas.cz, Tel.: 266 053 196
Rok sběru	2018

Počet záznamů: 1