Počet záznamů: 1
Regulators of Collagen Fibrillogenesis during Molar Development in the Mouse
- 1.
SYSNO ASEP 0478447 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Regulators of Collagen Fibrillogenesis during Molar Development in the Mouse Tvůrce(i) Žváčková, Ivana (UZFG-Y)
Matalová, Eva (UZFG-Y) RID
Lesot, Hervé (UZFG-Y)Číslo článku 554 Zdroj.dok. Frontiers in Physiology. - : Frontiers Research Foundation - ISSN 1664-042X
Roč. 8, č. 8 (2017)Poč.str. 14 s. Forma vydání Tištěná - P Jazyk dok. eng - angličtina Země vyd. CH - Švýcarsko Klíč. slova odontogenesis ; alveolar bone ; FACITs Vědní obor RIV EB - Genetika a molekulární biologie Obor OECD Developmental biology CEP GB14-37368G GA ČR - Grantová agentura ČR Institucionální podpora UZFG-Y - RVO:67985904 UT WOS 000406811900001 EID SCOPUS 85026783680 DOI 10.3389/fphys.2017.00554 Anotace Development of mammalian teeth and surrounding tissues includes time-space changes in the extracellular matrix composition and organization. This requires complex control mechanisms to regulate its synthesis and remodeling. Fibril-associated collagens with interrupted triple helices (FACITs) and a group of small leucine-rich proteoglycans (SLRPs) are involved in the regulation of collagen fibrillogenesis. Recently, collagen type XII and collagen type XIV, members of the FACITs family, were found in the peridentalmesenchyme contributing to alveolar bone formation. This study was designed to follow temporospatial expression of collagen types XIIa and XIVa in mouse first molar and adjacent tissues from embryonic day 13, when the alveolar bone becomes morphologically apparent around the molar tooth bud, until postnatal day 22, as the posteruption stage. The patterns of decorin, biglycan, and fibromodulin, all members of the SLRPs family and interacting with collagens XIIa and XIVa, were investigated simultaneously. The situation in the tooth was related to what happens in the alveolar bone, and both were compared to the periodontal ligament. The investigation provided a complex localization of the five antigens in soft tissues, the dental pulp, and periodontal ligaments, in the mineralized tissues, predentin/dentin and alveolar bone, and junction between soft and hard tissues. The results illustrated developmentally regulated and tissue-specific changes in the balance of the two FACITs and three SLRPs. Pracoviště Ústav živočišné fyziologie a genetiky Kontakt Jana Zásmětová, knihovna@iapg.cas.cz, Tel.: 315 639 554 Rok sběru 2018
Počet záznamů: 1