Počet záznamů: 1
New adenoviruses from new primate hosts - growing diversity reveals taxonomic weak points
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SYSNO ASEP 0475020 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název New adenoviruses from new primate hosts - growing diversity reveals taxonomic weak points Tvůrce(i) Dadáková, E. (CZ)
Chrudimský, Tomáš (BC-A) RID
Brožová, K. (CZ)
Modrý, David (BC-A) RID, ORCID
Celer, V. (CZ)
Hrazdilová, K. (CZ)Zdroj.dok. Molecular Phylogenetics and Evolution. - : Elsevier - ISSN 1055-7903
Roč. 107, February (2017), s. 305-307Poč.str. 3 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova adenovirus ; primate ; phylogeny ; taxonomy Vědní obor RIV EE - Mikrobiologie, virologie Obor OECD Microbiology Institucionální podpora BC-A - RVO:60077344 UT WOS 000394200500029 EID SCOPUS 85001948848 DOI 10.1016/j.ympev.2016.11.013 Anotace The knowledge of the closest human relatives of human adenoviruses (AdVs) such as adenoviruses found in nonhuman primates is still limited, despite the growing importance of adenoviruses in vaccine development, gene and cancer therapy. We examined 153 stool samples of 17 non-human primate species and detected adenoviral DNA sequences of DNA polymerase (DPOL) gene in 54 samples (35%), originating from 12 out of 17 primate species. We further sequenced 15 hexon gene fragments and based on the phylogenetic analysis we propose two new provisional species SAdV-H and SAdV-I. Our study shows extensive diversity of adenoviral strains forming separate clades often from closely related host species from old world monkeys suggesting the existence of new species of AdVs and shows the necessity for clear ICTV guidelines for final establishment of so far provisional AdV species. Pracoviště Biologické centrum (od r. 2006) Kontakt Dana Hypšová, eje@eje.cz, Tel.: 387 775 214 Rok sběru 2018
Počet záznamů: 1