Počet záznamů: 1
Molecular Mechanism of the Two-Component Suicidal Weapon of Neocapritermes taracua Old Workers
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SYSNO ASEP 0459003 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Molecular Mechanism of the Two-Component Suicidal Weapon of Neocapritermes taracua Old Workers Tvůrce(i) Bourguignon, T. (CZ)
Šobotník, J. (CZ)
Brabcová, Jana (UOCHB-X) RID
Sillam-Dusses, D. (FR)
Buček, Aleš (UOCHB-X) RID
Krasulová, Jana (UOCHB-X) RID
Vytisková, B. (CZ)
Demianova, Z. (AT)
Mareš, Michael (UOCHB-X) RID, ORCID
Roisin, Y. (BE)
Vogel, H. (DE)Zdroj.dok. Molecular Biology and Evolution. - : Oxford University Press - ISSN 0737-4038
Roč. 33, č. 3 (2016), s. 809-819Poč.str. 11 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova altruism ; colony defense ; termite ; Isoptera ; laccase Vědní obor RIV CE - Biochemie CEP LO1302 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy Institucionální podpora UOCHB-X - RVO:61388963 UT WOS 000371219500018 EID SCOPUS 84964467111 DOI 10.1093/molbev/msv273 Anotace In termites, as in many social insects, some individuals specialize in colony defense, developing diverse weaponry. As workers of the termite Neocapritermes taracua (Termitidae: Termitinae) age, their efficiency to perform general tasks decreases, while they accumulate defensive secretions and increase their readiness to fight. This defensive mechanism involves self-sacrifice through body rupture during which an enzyme, stored as blue crystals in dorsal pouches, converts precursors produced by the labial glands into highly toxic compounds. Here, we identify both components of this activated defense system and describe the molecular basis responsible for the toxicity of N. taracua worker autothysis. The blue crystals are formed almost exclusively by a specific protein named BP76. By matching N. taracua transcriptome databases with amino acid sequences, we identified BP76 to be a laccase. Following autothysis, the series of hydroquinone precursors produced by labial glands get mixed with BP76, resulting in the conversion of relatively harmless hydroquinones into toxic benzoquinone analogues. Neocapritermes taracua workers therefore rely on a two-component activated defense system, consisting of two separately stored secretions that can react only after suicidal body rupture, which produces a sticky and toxic cocktail harmful to opponents. Pracoviště Ústav organické chemie a biochemie Kontakt asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434 Rok sběru 2017
Počet záznamů: 1