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Fancy a gene? A surprisingly complex evolutionary history/nof peroxiredoxins
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SYSNO ASEP 0453266 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Ostatní články Název Fancy a gene? A surprisingly complex evolutionary history/nof peroxiredoxins Tvůrce(i) Zíková, Alena (BC-A) RID, ORCID
Oborník, Miroslav (BC-A) RID, ORCID
Lukeš, Julius (BC-A) RID, ORCIDZdroj.dok. Microbial cell. - : Shared Science Publishers - ISSN 2311-2638
Roč. 2, č. 2 (2015), s. 33-37Poč.str. 5 s. Forma vydání Online - E Jazyk dok. eng - angličtina Země vyd. AT - Rakousko Klíč. slova horizontal gene transfer ; Apicomplexa ; endosymbiont ; Plasmodium ; Chromera ; peroxiredoxin ; oxidative stress Vědní obor RIV EB - Genetika a molekulární biologie Institucionální podpora BC-A - RVO:60077344 DOI https://doi.org/10.15698/mic2015.02.189 Anotace While the phylum Apicomplexa includes “only” several/nthousand described species of obligatory parasites of animals, it may in fact be the most specious group of parasitic protists with over a million species [1]. The best known representatives are Plasmodium spp., Toxoplasma gondii and Cryptosporidium spp., which belong to the most important and widespread human parasites exacting an enormous disease burden. On the other hand, dinoflagellates and colpodellids, which are monophyletic with the apicomplexans, are ecologically highly significant, as they belong to the most abundant marine protists [2]. As the common ancestor of these groups was most likely a freeliving photosynthesizing protist, one wonders, which evolutionary forces contributed to the dramatic transition of some of its descendants into the arguably most successful/nintracellular parasites? Although a range of various processes and mechanisms contributed to this transition, most likely it also involved an acquisition of genes via horizontal gene transfer (HGT), which might have provided typical characteristics of a parasitic cell, such as immune escape, nutritional dependence and the capacity to invade other cells. Pracoviště Biologické centrum (od r. 2006) Kontakt Dana Hypšová, eje@eje.cz, Tel.: 387 775 214 Rok sběru 2016
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