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Fancy a gene? A surprisingly complex evolutionary history/nof peroxiredoxins

SYSNO ASEP	0453266
Druh ASEP	J - Článek v odborném periodiku
Zařazení RIV	J - Článek v odborném periodiku
Poddruh J	Ostatní články
Název	Fancy a gene? A surprisingly complex evolutionary history/nof peroxiredoxins
Tvůrce(i)	Zíková, Alena (BC-A)_{RID, ORCID} Oborník, Miroslav (BC-A)_{RID, ORCID} Lukeš, Julius (BC-A)_{RID, ORCID}
Zdroj.dok.	Microbial cell. - : Shared Science Publishers Roč. 2, č. 2 (2015), s. 33-37
Poč.str.	5 s.
Forma vydání	Online - E
Jazyk dok.	eng - angličtina
Země vyd.	AT - Rakousko
Klíč. slova	horizontal gene transfer ; Apicomplexa ; endosymbiont ; Plasmodium ; Chromera ; peroxiredoxin ; oxidative stress
Vědní obor RIV	EB - Genetika a molekulární biologie
Institucionální podpora	BC-A - RVO:60077344
DOI	10.15698/mic2015.02.189
Anotace	While the phylum Apicomplexa includes “only” several/nthousand described species of obligatory parasites of animals, it may in fact be the most specious group of parasitic protists with over a million species [1]. The best known representatives are Plasmodium spp., Toxoplasma gondii and Cryptosporidium spp., which belong to the most important and widespread human parasites exacting an enormous disease burden. On the other hand, dinoflagellates and colpodellids, which are monophyletic with the apicomplexans, are ecologically highly significant, as they belong to the most abundant marine protists [2]. As the common ancestor of these groups was most likely a freeliving photosynthesizing protist, one wonders, which evolutionary forces contributed to the dramatic transition of some of its descendants into the arguably most successful/nintracellular parasites? Although a range of various processes and mechanisms contributed to this transition, most likely it also involved an acquisition of genes via horizontal gene transfer (HGT), which might have provided typical characteristics of a parasitic cell, such as immune escape, nutritional dependence and the capacity to invade other cells.
Pracoviště	Biologické centrum (od r. 2006)
Kontakt	Dana Hypšová, eje@eje.cz, Tel.: 387 775 214
Rok sběru	2016

Počet záznamů: 1