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The utility of three-dimensional optical projection tomography in nerve injection injury imaging
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SYSNO ASEP 0446968 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název The utility of three-dimensional optical projection tomography in nerve injection injury imaging Tvůrce(i) Cvetko, E. (SI)
Čapek, Martin (FGU-C) RID, ORCID
Damjanovska, M. (SI)
Reina, M. A. (ES)
Eržen, I. (SI)
Stopar-Pintarič, T. (SI)Zdroj.dok. Anaesthesia - ISSN 0003-2409
Roč. 70, č. 8 (2015), s. 939-947Poč.str. 9 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova optical projection tomography ; 3D nerve visualization ; nerve disruption Vědní obor RIV EA - Morfologické obory a cytologie CEP GA13-12412S GA ČR - Grantová agentura ČR LH13028 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy Institucionální podpora FGU-C - RVO:67985823 UT WOS 000357731200008 EID SCOPUS 84936845897 DOI 10.1111/anae.13066 Anotace The objective of this study was to evaluate the ability of optical projection tomography to discern the nerve microarchitecture and injection injury in three dimensions. Five piglets were studied, whose median and lingual nerves were unilaterally injected post mortem with preset volumes of local anaesthetic, excised and subsequently made transparent with benzyl alcohol benzyl benzoate. Images were captured in three dimensions. The same contralateral nerves were used as controls. Using optical projection tomography, we observed differences between the internal organisation of the median and the lingual nerves, which potentially explain the variations in their susceptibility to injury. This was demonstrated in three dimensions as a disruption to the fascicles in the lingual nerve, and their displacement in the median nerve. This new technology offers potential for studying nerve microarchitecture topography and its tolerance to injection injury Pracoviště Fyziologický ústav Kontakt Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Rok sběru 2016
Počet záznamů: 1