Počet záznamů: 1
Influence of inhaled manganese oxides nanoparticles on mass of internal organs in mice
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SYSNO ASEP 0445841 Druh ASEP C - Konferenční příspěvek (mezinárodní konf.) Zařazení RIV D - Článek ve sborníku Název Influence of inhaled manganese oxides nanoparticles on mass of internal organs in mice Tvůrce(i) Zeman, T. (CZ)
Dočekal, Bohumil (UIACH-O) RID, ORCID
Mikuška, Pavel (UIACH-O) RID, ORCID
Buchtová, Marcela (UZFG-Y) RID, ORCID
Míšek, Ivan (UZFG-Y)
Šerý, Omar (UZFG-Y) RID
Večeřa, Zbyněk (UIACH-O) RIDCelkový počet autorů 7 Zdroj.dok. NANOCON 2014, 6th International Conference. - Ostrava : TANGER Ltd, 2014 - ISBN 978-80-87294-53-6 Rozsah stran s. 686-691 Poč.str. 6 s. Forma vydání Tištěná - P Akce NANOCON International Conference /6./ Datum konání 05.11.2014-07.11.2014 Místo konání Brno Země CZ - Česká republika Typ akce WRD Jazyk dok. eng - angličtina Země vyd. CZ - Česká republika Klíč. slova inhaled nanoparticles ; manganese oxides nanoparticles ; changes in internal organ mass of mice ; long-term inhalation experiment Vědní obor RIV CB - Analytická chemie, separace CEP GBP503/12/G147 GA ČR - Grantová agentura ČR GAP503/11/2315 GA ČR - Grantová agentura ČR Institucionální podpora UIACH-O - RVO:68081715 ; UZFG-Y - RVO:67985904 UT WOS 000350636300118 Anotace Results of the statistical analysis of a long-term inhalation experiment on laboratory mice are presented. During 17 weeks of the experiment, the experimental group was exposed to inhaled manganese oxides nanoparticles. Manganese oxides (MnO center dot Mn2O3) nanoparticles (MnONPs) were synthesized continuously via aerosol route in a hot wall tube flow reactor using a thermal decomposition of metal organic precursor manganese(II) acetylacetonate in the flow tube reactor (in vertical position) at temperature 750 degrees C in the presence of 30 vol% of oxygen. The concentration of produced MnONPs at the reactor output was in the range 1-3 x 10(7) particles/cm(3) and the size of generated nanoparticles MnO center dot Mn2O3 was in the range 7-50 nm. Before entering the inhalation chamber, MnONPs in the mixture of N-2, O-2 and air (at total flow rate of 3 L/min) were further diluted using filtrated humidified air (20 L/min) at temperature 21 degrees C resulting in the MnONPs concentration 2 x 10(6) particles/cm(3). At regular time intervals the mass of selected internal organs of mice from both experimental and control group was assessed. It has been proven that inhaled nanoparticles are able to influence the mass of internal organs of mice. Statistically significantly lower mass of kidneys, liver and spleen and higher mass of pancreas have been found in the experimental group compared to the control group. Pracoviště Ústav analytické chemie Kontakt Iveta Drobníková, drobnikova@iach.cz, Tel.: 532 290 234 Rok sběru 2016
Počet záznamů: 1