Počet záznamů: 1
The Lithiation Reactivity and Selectivity of Differentially Branched Alkyldiphenylphosphine Oxides - A Simple and Versatile Approach to ortho-Functionalized Arylphosphine Oxides
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SYSNO ASEP 0443900 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název The Lithiation Reactivity and Selectivity of Differentially Branched Alkyldiphenylphosphine Oxides - A Simple and Versatile Approach to ortho-Functionalized Arylphosphine Oxides Tvůrce(i) Mahamulkar, Shraddha G. (UOCHB-X)
Císařová, I. (CZ)
Jahn, Ullrich (UOCHB-X) ORCIDCelkový počet autorů 3 Zdroj.dok. Advanced Synthesis & Catalysis. - : Wiley - ISSN 1615-4150
Roč. 357, č. 4 (2015), s. 793-799Poč.str. 7 s. Jazyk dok. eng - angličtina Země vyd. DE - Německo Klíč. slova lithiation ; nucleophilic substitution ; organolithium reagents ; phosphine oxides ; phosphine-borane complexes Vědní obor RIV CC - Organická chemie CEP GAP207/11/1598 GA ČR - Grantová agentura ČR Institucionální podpora UOCHB-X - RVO:61388963 UT WOS 000351222700021 EID SCOPUS 84924325890 DOI 10.1002/adsc.201400861 Anotace Alkyldiphenylphosphine oxides typically undergo alpha-deprotonation with alkyllithium reagents. Here, the lithiation of differentially branched alkyl-diphenylphosphine oxides was investigated and a diverse, but predictable reactivity was found. gamma-Branched derivatives undergo selective directed ortho-metalation (DoM) using butyllithium and TMEDA as an additive. With decreasing degree of gamma-branching alpha-lithiation becomes predominant. The ortho-phosphinoyllithium intermediates are subject to functionalization and C-C bond forming reactions, thus providing a convenient approach to new phosphine oxides and phosphine-borane complexes, which have a good potential for an approach to new ligands for catalysis. Pracoviště Ústav organické chemie a biochemie Kontakt asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434 Rok sběru 2016
Počet záznamů: 1