Počet záznamů: 1
Biophysical pathology in cancer transformation
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SYSNO ASEP 0440282 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Ostatní články Název Biophysical pathology in cancer transformation Tvůrce(i) Pokorný, Jiří (URE-Y) RID
Pokorný, Jan (FZU-D) RID, ORCIDZdroj.dok. Journal of Clinical & Experimental Oncology - ISSN 2324-9110
S1, Nov (2013), s. 1-9Poč.str. 9 s. Forma vydání Online - E Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova cancer biophysics ; Warburg effect ; reverse Warburg effect ; biological electrodynamics ; coherent states Vědní obor RIV BO - Biofyzika CEP GAP102/11/0649 GA ČR - Grantová agentura ČR Institucionální podpora FZU-D - RVO:68378271 ; URE-Y - RVO:67985882 DOI 10.4172/2324-9110.S1-003 Anotace Energy supply to biological systems excites and sustains the state far from thermodynamic equilibrium, a necessary condition for life. Energy processing by mitochondria forms a strong static electric field which causes ordering of water, establishing conditions for generation of the electromagnetic field by microtubules. Disturbances of the energy supply system result in pathological states (disturbances of oxidative metabolism in cancer). Due to nonlinear properties of microtubule oscillations the frequency spectra of the electromagnetic field generated by cancer cells may be rebuilt and shifted in comparison to standard frequency spectra of the tissue. Tissue interactions are changed. A cancer cell disassociates itself from interactions with healthy cells, evades the regulation and control of tissue, and may move outside its assigned position. Mitochondrial dysfunction in cancers is distinct from the normal function in healthy cells and should be targeted for selective treatment. Pracoviště Fyzikální ústav Kontakt Kristina Potocká, potocka@fzu.cz, Tel.: 220 318 579 Rok sběru 2015
Počet záznamů: 1