Počet záznamů: 1

Contribution of Ca2+-Dependent Cl- Channels to Norepinephrine-Induced Contraction of Femoral Artery Is Replaced by Increasing EDCF Contribution during Ageing

SYSNO ASEP	0428048
Druh ASEP	J - Článek v odborném periodiku
Zařazení RIV	J - Článek v odborném periodiku
Poddruh J	Článek ve WOS
Název	Contribution of Ca2+-Dependent Cl- Channels to Norepinephrine-Induced Contraction of Femoral Artery Is Replaced by Increasing EDCF Contribution during Ageing
Tvůrce(i)	Líšková, Silvia (FGU-C) Petrová, M. (SK) Karen, Petr (FGU-C) Behuliak, Michal (FGU-C)_{RID, ORCID} Zicha, Josef (FGU-C)_{RID, ORCID, SAI}
Zdroj.dok.	BioMed Research International. - : Hindawi - ISSN 2314-6133 Roč. 2014, č. 2014 (2014), s. 289361
Poč.str.	9 s.
Jazyk dok.	eng - angličtina
Země vyd.	US - Spojené státy americké
Klíč. slova	calcium-dependent chloride channels ; endothelium-derived contracting factor ; ageing
Vědní obor RIV	FA - Kardiovaskulární nemoci vč. kardiochirurgie
CEP	GAP304/12/0259 GA ČR - Grantová agentura ČR
Institucionální podpora	FGU-C - RVO:67985823
UT WOS	000332565500001
EID SCOPUS	84897882006
DOI	10.1155/2014/289361
Anotace	The activation of calcium-dependent chloride channels during norepinephrine-induced contraction of vascular smooth muscle was suggested to depolarize cell membrane and to increase calcium entry. Hypertension and ageing are associated with altered calcium handling including possible activation of calcium-dependent chloride channels. Our study was aimed to determine calcium -dependent chloride channels contribution to norepinephrine-induced contraction during hypertension and ageing. We have found that contribution of calcium -dependent chloride channels to norepinephrine-induced contraction diminished with age, hypertension development, and/or NO synthesis inhibition
Pracoviště	Fyziologický ústav
Kontakt	Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
Rok sběru	2015

Počet záznamů: 1