Počet záznamů: 1
Circular Dichroism: Theory and Spectroscopy
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SYSNO ASEP 0376811 Druh ASEP M - Kapitola v monografii Zařazení RIV C - Kapitola v knize Název Vibrational Circular Dichroism Studies of Biological Macromolecules and their Complexes Tvůrce(i) Polyanichko, A. M. (RU)
Andrushchenko, Valery (UOCHB-X) RID, ORCID
Bouř, Petr (UOCHB-X) RID, ORCID
Wieser, H. (CA)Celkový počet autorů 4 Zdroj.dok. Circular Dichroism: Theory and Spectroscopy. - Hauppauge, NY : Nova Science Publishers, Inc, 2012 / Rodgers D. S. - ISBN 978-1-61122-522-8 Rozsah stran s. 67-126 Poč.str. 60 s. Poč.str.knihy 500 Forma vydání Online - E Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova vibrational circular dichroism (VCD) ; proteins ; nucleic acids ; peptides ; spectra simulations Vědní obor RIV CF - Fyzikální chemie a teoretická chemie CEP GAP208/10/0559 GA ČR - Grantová agentura ČR IAA400550702 GA AV ČR - Akademie věd CEZ AV0Z40550506 - UOCHB-X (2005-2011) Anotace Vibrational circular dichroism (VCD) being a relatively new spectroscopic technique is quite promising for studying of biological molecules and their complexes. It combines conformational sensitivity of electronic circular dichroism (CD, or ECD) with extensive local mode information provided by the vibrational spectroscopy. Another advantage of VCD over ECD is its applicability to complexes of biological macromolecules, which would cause considerable light scattering in the UV region. This makes VCD a particularly useful tool for the investigation and characterization of various molecular structures. Here, we overview the theoretical background, discuss some practical aspects of VCD application to biological molecules, and list major spectral features encountered in the most common types of DNA and protein secondary structures. We also describe VCD applications to structural and conformational analysis of biological macromolecules and their complexes, insluding those with metal ions and drugs. In the end of the chapter, we outline some of the current state of the art methodology for computations of VCD spectra of large biopolymers. Pracoviště Ústav organické chemie a biochemie Kontakt asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434 Rok sběru 2013 Elektronická adresa https://www.novapublishers.com/catalog/product_info.php?products_id=32793
Počet záznamů: 1