Počet záznamů: 1
Ileal Peyer's Patches Are Not Necessary for Systemic B Cell Development and Maintenance and Do Not Contribute Significantly to the Overall B Cell Pool in Swine
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SYSNO ASEP 0370664 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Ileal Peyer's Patches Are Not Necessary for Systemic B Cell Development and Maintenance and Do Not Contribute Significantly to the Overall B Cell Pool in Swine Tvůrce(i) Šinkora, Marek (MBU-M) RID, ORCID
Štěpánová, Kateřina (MBU-M) ORCID
Butler, J. (US)
Francis, D. (US)
Santiago-Mateo, K. (US)
Potočková, Hana (MBU-M)
Kárová, Kristýna (MBU-M)
Šinkorová, Jana (MBU-M) RID, ORCIDZdroj.dok. Journal of Immunology. - : American Association of Immunologists - ISSN 0022-1767
Roč. 187, č. 10 (2011), s. 5150-5161Poč.str. 12 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova ANTIBODY REPERTOIRE DEVELOPMENT ; LYMPHOID-TISSUES ; NEONATAL PIGLETS Vědní obor RIV EC - Imunologie CEP ME09089 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy GAP502/10/0038 GA ČR - Grantová agentura ČR CEZ AV0Z50200510 - MBU-M (2005-2011) UT WOS 000296767300024 DOI 10.4049/jimmunol.1101879 Anotace Based on studies of sheep, the ileal Peyer’s patches (IPP) have been regard as a type of primary lymphoid tissue similar to the bursa of Fabricius in chicken. Since bursectomy results in B cell deficiency, we wondered if resection of the IPP of piglets would have a similar effect. Comparison of IPP resected, surgical shams and untreated germ-free piglets, all of which were later colonized with a defined commensal flora demonstrates that resection of the IPP did not alter the level and phenotype of B and T cells in lymphoid tissues and the blood during 10 weeks after surgery Pracoviště Mikrobiologický ústav Kontakt Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Rok sběru 2012
Počet záznamů: 1