Počet záznamů: 1

Development of ovarian hyperstimulation syndrome: interrogation of key proteins and biological processes in human follicular fluid of women undergoing in vitro fertilization

SYSNO ASEP	0368287
Druh ASEP	J - Článek v odborném periodiku
Zařazení RIV	J - Článek v odborném periodiku
Poddruh J	Článek ve WOS
Název	Development of ovarian hyperstimulation syndrome: interrogation of key proteins and biological processes in human follicular fluid of women undergoing in vitro fertilization
Tvůrce(i)	Jarkovská, Karla (UZFG-Y)_RID Skalníková, Helena (UZFG-Y)_{RID, ORCID} Halada, Petr (MBU-M)_{RID, ORCID} Hrabáková, Rita (UZFG-Y)_{RID, ORCID} Moos, J. (CZ) Rezábek, K. (CZ) Gadher, S. J. (US) Kovářová, Hana (UZFG-Y)_{RID, ORCID}
Celkový počet autorů	8
Zdroj.dok.	Molecular Human Reproduction - ISSN 1360-9947 Roč. 17, č. 11 (2011), s. 679-692
Poč.str.	14 s.
Jazyk dok.	eng - angličtina
Země vyd.	GB - Velká Británie
Klíč. slova	biomarkers ; computer modelling ; human follicular fluid
Vědní obor RIV	FK - Gynekologie a porodnictví
CEZ	AV0Z50450515 - UZFG-Y (2005-2011)
	AV0Z50200510 - MBU-M (2005-2011)
UT WOS	000296132700003
DOI	10.1093/molehr/gar047
Anotace	Ovarian hyperstimulation syndrome (OHSS) is an iatrogenic complication and potentially life-threatening condition resulting from excessive ovarian stimulation during assisted reproductive technologies. Our aim was to identify candidate proteins in follicular fluid (FF) using various proteomic approaches which may help to identify patients at risk of OHSS. We analysed the proteome alterations in FF from patients suffering from severe forms of OHSS (OHSS+) compared with a control group of women without or with only mild signs of OHSS (OHSS-). The 12 abundant proteins of FF were removed using an immunoaffinity system. Pools of remaining depleted proteins were applied to the two-dimensional (2D) electrophoresis and 2D liquid chromatography and proteins in differentially expressed protein spots/fractions were identified by mass spectrometry.
Pracoviště	Ústav živočišné fyziologie a genetiky
Kontakt	Jana Zásmětová, knihovna@iapg.cas.cz, Tel.: 315 639 554
Rok sběru	2012

Počet záznamů: 1