Počet záznamů: 1
Intra- and Interindividual Variability in Lymphocyte Chromosomal Aberrations: Implications for Cancer Risk Assessment
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SYSNO ASEP 0365858 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Intra- and Interindividual Variability in Lymphocyte Chromosomal Aberrations: Implications for Cancer Risk Assessment Tvůrce(i) Peters, S. (NL)
Portengen, L. (NL)
Bonassi, S. (IT)
Šrám, Radim (UEM-P) RID
Vermeulen, R. (NL)Zdroj.dok. American Journal of Epidemiology - ISSN 0002-9262
Roč. 174, č. 4 (2011), s. 490-493Poč.str. 4 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova chromosomal aberrations frequency ; cancer risk assessment Vědní obor RIV DN - Vliv životního prostředí na zdraví CEZ AV0Z50390512 - UEM-P (2005-2011) UT WOS 000293595300013 EID SCOPUS 80051512974 DOI 10.1093/aje/kwr114 Anotace Chromosomal aberration (CA) frequency in peripheral lymphocytes of healthy individuals has been found to be predictive of future cancer risk. Intra- and interindividual variability in CA frequency was determined. From a pooled database comprising 11 national cohorts (1965-2002) the authors included 9,433 blood samples from 3,550 subjects with at least one repeated CA measurement. The generalized concordance correlation coeff. of 0.19 was low, indicating high intraindividual variability compared with interindividual variability, resulting in a high likelihood of missclassification. The authors stated that the relation between CA frequency and future cancer risk has probably been underestimated in previous studies. Pracoviště Ústav experimentální medicíny Kontakt Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Rok sběru 2012
Počet záznamů: 1