Počet záznamů: 1  

Relation of genetic phylogeny and geographical distance of tick-borne encephalitis virus in central Europe

  1. 1.
    SYSNO ASEP0364901
    Druh ASEPJ - Článek v odborném periodiku
    Zařazení RIVJ - Článek v odborném periodiku
    Poddruh JČlánek ve WOS
    NázevRelation of genetic phylogeny and geographical distance of tick-borne encephalitis virus in central Europe
    Tvůrce(i) Weidmann, M. (NL)
    Růžek, Daniel (BC-A) RID, ORCID
    Křivanec, K. (CZ)
    Zoeller, G. (DE)
    Essbauer, S. (DE)
    Pfeffer, M. (DE)
    Zanotto, P. M. de A. (BR)
    Hufert, F.T. (NL)
    Dobler, G. (DE)
    Zdroj.dok.Journal of General Virology. - : Microbiology Society - ISSN 0022-1317
    Roč. 92, Part 8 (2011), 1906-1916
    Poč.str.11 s.
    Jazyk dok.eng - angličtina
    Země vyd.GB - Velká Británie
    Klíč. slovaIXODES-RICINUS ; NATURAL FOCI ; ROE DEER ; ENDEMIC AREA ; RUSSIA ; FLAVIVIRUSES ; EVOLUTION ; VECTOR ; SWEDEN ; JAPAN
    Vědní obor RIVEE - Mikrobiologie, virologie
    CEPGPP302/10/P438 GA ČR - Grantová agentura ČR
    GAP502/11/2116 GA ČR - Grantová agentura ČR
    LC06009 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy
    CEZAV0Z60220518 - PAU-O, BC-A (2005-2011)
    UT WOS000293488800020
    DOI10.1099/vir.0.032417-0
    AnotaceTick-borne encephalitis virus (TBEV) is the most important arboviral agent causing disease of the central nervous system in central Europe. In this study, 61 TBEV E gene sequences derived from 48 isolates from the Czech Republic (CR), and 4 isolates and 9 TBEV strains detected in ticks from Germany (1954 to 2009), were sequenced and subjected to phylogenetic and Bayesian phylodynamic. The general Eurasian continental east-to-west pattern of the spread of TBEV was confirmed at the regional level but is interlaced with spreading that arises because of local geography and anthropogenic influence. This spread is reflected by the disease pattern in the CR that has been observed since 1991. The overall evolutionary rate was estimated to be approximately 8x10(-4) substitutions per nucleotide per year. The analysis of the TBEV E genes of 11 strains isolated at one natural focus in Zd'ar Kaplice proved for the first time that TBEV is indeed subject to local evolution.
    PracovištěBiologické centrum (od r. 2006)
    KontaktDana Hypšová, eje@eje.cz, Tel.: 387 775 214
    Rok sběru2012
Počet záznamů: 1  

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