Počet záznamů: 1
Biomarkers of exposure and effect – interpretation for human risk
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SYSNO ASEP 0363581 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Biomarkers of exposure and effect – interpretation for human risk Tvůrce(i) Šrám, Radim (UEM-P) RID
Binková, B. (CZ)
Beskid, Olena (UEM-P)
Milcová, Alena (UEM-P)
Rössner, P. (CZ)
Rössner ml., Pavel (UEM-P) RID, ORCID
Rössnerová, Andrea (UEM-P) RID
Solanský, I. (CZ)
Topinka, Jan (UEM-P) RID, ORCIDZdroj.dok. Air Quality, Atmosphere and Health (AQAH) - ISSN 1873-9318
Roč. 4, č. 3 (2011), s. 161-167Poč.str. 9 s. Jazyk dok. eng - angličtina Země vyd. NL - Nizozemsko Klíč. slova personal monitoring ; benzo[a]pyrene ; carcinogenic polycyclic aromatic hydrocarbons Vědní obor RIV DN - Vliv životního prostředí na zdraví CEP SL/5/160/05 GA MŽP - Ministerstvo životního prostředí SP/1B3/8/08 GA MŽP - Ministerstvo životního prostředí CEZ AV0Z50390512 - UEM-P (2005-2011) UT WOS 000309479900002 EID SCOPUS 80051694260 DOI 10.1007/s11869-011-0133-8 Anotace The effect of exposure to carcinogenic PAHs adsorbed onto respirable air particles on DNA adducts and chromosomal aberrations was repeatedly studied in groups of policemen and bus drivers from Prague, Czech Republic. Personal exposure was evaluated using personal samplers during working shifts. DNA adducts were analyzed in lymphocytes by the 32P-postlabeling assay and chromosomal aberrations by conventional cytogenetic analysis and by fluorescent in situ hybridization (FISH). The studies suggest that the environmental exposure of nonsmokers to concentrations higher than 1 ng B[a]P/m3 represents a risk to DNA damage, as indicated by an increase in DNA adducts and in the genomic frequency of translocations determined by FISH. Pracoviště Ústav experimentální medicíny Kontakt Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Rok sběru 2012
Počet záznamů: 1