Počet záznamů: 1

Rapid changes in gene expression: DNA determinants of promoter regulation by the

SYSNO ASEP	0360790
Druh ASEP	J - Článek v odborném periodiku
Zařazení RIV	J - Článek v odborném periodiku
Poddruh J	Článek ve WOS
Název	Rapid changes in gene expression: DNA determinants of promoter regulation by the
Tvůrce(i)	Sojka, Luděk (MBU-M) Kouba, Tomáš (MBU-M) Barvík, I. (CZ) Šanderová, Hana (MBU-M)_{RID, ORCID} Maderová, Zdeňka (MBU-M) Jonák, Jiří (MBU-M) Krásný, Libor (MBU-M)_{RID, ORCID}
Zdroj.dok.	Nucleic Acids Research. - : Oxford University Press - ISSN 0305-1048 Roč. 39, č. 11 (2011), s. 4598-4611
Poč.str.	14 s.
Jazyk dok.	eng - angličtina
Země vyd.	GB - Velká Británie
Klíč. slova	RIBOSOMAL-RNA TRANSCRIPTION ; ILV-LEU OPERON ; CHAIN AMINO-ACIDS
Vědní obor RIV	EE - Mikrobiologie, virologie
CEP	2B06065 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy
CEZ	AV0Z50200510 - MBU-M (2005-2011)
UT WOS	000291755000013
DOI	10.1093/nar/gkr032
Anotace	In bacteria, rapid changes in gene expression can be achieved by affecting the activity of RNA polymerase with small molecule effectors during transcription initiation. An important small molecule effector is the initiating nucleoside triphosphate (iNTP). At some promoters, an increasing iNTP concentration stimulates promoter activity, while a decreasing concentration has the opposite effect. Ribosomal RNA (rRNA) promoters from Grampositive Bacillus subtilis are regulated by the concentration of their iNTP. Yet, the sequences of these promoters do not emulate the sequence characteristics of [iNTP]-regulated rRNA promoters of Gram-negative Escherichia coli. Here, we identified the 30-promoter region, corresponding to the transcription bubble, as key for B. subtilis rRNA promoter regulation via the concentration of the iNTP
Pracoviště	Mikrobiologický ústav
Kontakt	Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231
Rok sběru	2012

Počet záznamů: 1