Počet záznamů: 1
Results and Problems in Cell Differentiation
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SYSNO ASEP 0360511 Druh ASEP M - Kapitola v monografii Zařazení RIV C - Kapitola v knize Název The Role of RanGTP Gradient in Vertebrate Oocyte Maturation Tvůrce(i) Kalab, P. (US)
Šolc, Petr (UZFG-Y) RID, ORCID
Motlík, Jan (UZFG-Y) RID, ORCIDCelkový počet autorů 3 Zdroj.dok. Results and Problems in Cell Differentiation. - Heidelberg : Springer, 2011 - ISBN 978-3-642-19065-0 Rozsah stran s. 235-267 Poč.str. 33 s. Poč.výt. 1000 Poč.str.knihy 588 Jazyk dok. eng - angličtina Země vyd. DE - Německo Klíč. slova RanGTP ; Oocyte Vědní obor RIV EB - Genetika a molekulární biologie CEP GC301/09/J036 GA ČR - Grantová agentura ČR ME08030 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy CEZ AV0Z50450515 - UZFG-Y (2005-2011) UT WOS 000292219600012 DOI 10.1007/978-3-642-19065-0_12 Anotace The maturation of vertebrate oocyte into haploid gamete, the egg, consists of two specialized asymmetric cell divisions with no intervening S-phase. Ran GTPase has an essential role in relaying the active role of chromosomes in their own segregation by the meiotic process. In addition to its conserved role as a key regulator of macromolecular transport between nucleus and cytoplasm, Ran has important functions during cell division, including in mitotic spindle assembly and in the assembly of nuclear envelope at the exit from mitosis. The cellular functions of Ran are mediated by RanGTP interactions with nuclear transport receptors (NTRs) related to importin b and depend on the existence of chromosome-centered RanGTP gradient. Live imaging with FRET biosensors indeed revealed the existence of RanGTP gradient throughout mouse oocyte maturation. Pracoviště Ústav živočišné fyziologie a genetiky Kontakt Jana Zásmětová, knihovna@iapg.cas.cz, Tel.: 315 639 554 Rok sběru 2012
Počet záznamů: 1