Počet záznamů: 1
Distribution of BODIPY-labelled phosphatidylethanolamines in lipid bilayers exhibiting different curvatures
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SYSNO ASEP 0360229 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Distribution of BODIPY-labelled phosphatidylethanolamines in lipid bilayers exhibiting different curvatures Tvůrce(i) Šachl, Radek (UFCH-W) RID, ORCID
Mikhalyov, I. (RU)
Gretskaya, N. (RU)
Olžyńska, Agnieszka (UFCH-W) RID
Hof, Martin (UFCH-W) RID, ORCID
Johansson, B.-A. (SE)Zdroj.dok. Physical Chemistry Chemical Physics. - : Royal Society of Chemistry - ISSN 1463-9076
Roč. 13, č. 24 (2011), s. 11694-11701Poč.str. 8 s. Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova BODIPY-labelled phosphatidylethanolamines ; lipid bilayers ; physical chemistry Vědní obor RIV CF - Fyzikální chemie a teoretická chemie CEP GAP208/10/1090 GA ČR - Grantová agentura ČR LC06063 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy CEZ AV0Z40400503 - UFCH-W (2005-2011) UT WOS 000291395200030 DOI 10.1039/C1CP20608G Anotace In this paper we have investigated the behaviour of newly synthesised mono-palmitoyl- and dipalmitoyl-phosphatidylethanolamine probes (abbreviated as mPE and dPE, respectively) labelled in the polar headgroup region by either the FL-BODIPY or the 564/570-BODIPY fluorophore and solubilised in lipid systems that exhibit different curvatures. Because of the bulky BODIPY-groups, the monoacyl-form derivatives have a conic-like shape, whereas that for the diacyl derivatives is rather cylindrical. A careful analysis of time-resolved resonance energy transfer experiments by means of analytical models as well as Monte Carlo simulations shows that the mPE derivatives have a comparable affinity to highly curved bilayer regions (torroidal pores formed by magainin-2 in lipid bilayers, or the rims of discoid bicelles) and to planar bilayer regions (i.e. the flat region of lipid bilayers and bicelles). Pracoviště Ústav fyzikální chemie J.Heyrovského Kontakt Michaela Knapová, michaela.knapova@jh-inst.cas.cz, Tel.: 266 053 196 Rok sběru 2012
Počet záznamů: 1