Počet záznamů: 1
Restoration of spermatogenesis after transplantation of c-Kit positive testicular cells in the fowl
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SYSNO ASEP 0355186 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Restoration of spermatogenesis after transplantation of c-Kit positive testicular cells in the fowl Tvůrce(i) Trefil, P. (CZ)
Bakst, M.R. (US)
Yan, H. (CN)
Hejnar, Jiří (UMG-J) RID
Kalina, J. (CZ)
Mucksová, J. (CZ)Zdroj.dok. Theriogenelogy. - : Elsevier - ISSN 0093-691X
Roč. 74, č. 9 (2010), s. 1670-1676Poč.str. 7 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova chicken ; transplantation ; c-Kit receptor Vědní obor RIV EB - Genetika a molekulární biologie CEP GA523/07/1171 GA ČR - Grantová agentura ČR CEZ AV0Z50520514 - UMG-J (2005-2011) UT WOS 000284499600019 DOI 10.1016/j.theriogenology.2010.07.002 Anotace Transplantation of male germ line cells Into sterilized recipients has been used in mammals for conventional breeding as well as for transgenesis We have previously adapted this approach for the domestic chicken and we present now an improvement of the germ cell transplantation technique by using an enriched subpopulation of c-Kit positive spermatogonia as donor cells Dispersed c-Kit positive testicular cells from 16 to 17 week-old pubertal donors were transplanted by injection directly into the testes of recipient males sterilized by repeated gamma irradiation We describe the repopulation of the recipient s testes with c Kit positive donor testicular cells, which resulted in the production of functional heterologous spermatozoa Pracoviště Ústav molekulární genetiky Kontakt Nikol Škňouřilová, nikol.sknourilova@img.cas.cz, Tel.: 241 063 217 Rok sběru 2011
Počet záznamů: 1