Počet záznamů: 1
Structure and antitumour activity of fucoidan isolated from sporophyll of Korean brown seaweed Undaria pinnatifida
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SYSNO ASEP 0352928 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Structure and antitumour activity of fucoidan isolated from sporophyll of Korean brown seaweed Undaria pinnatifida Tvůrce(i) Synytsya, A. (CZ)
Kim, W. J. (KR)
Kim, S. M. (KR)
Pohl, Radek (UOCHB-X) RID, ORCID
Synytsya, Al. (CZ)
Kvasnička, F. (CZ)
Čopíková, J. (CZ)
Park, Y. I. (KR)Celkový počet autorů 8 Zdroj.dok. Carbohydrate Polymers. - : Elsevier - ISSN 0144-8617
Roč. 81, č. 1 (2010), s. 41-48Poč.str. 8 s. Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova fucoidan from sporophyll Undaria pinnatifida ; structure ; antitumour activity Vědní obor RIV CC - Organická chemie CEZ AV0Z40550506 - UOCHB-X (2005-2011) UT WOS 000277953500007 DOI 10.1016/j.carbpol.2010.01.052 Anotace Fucoidan from the sporophyll (Miyeokgui) Korean brown seaweeds Undaria pinnatifida was isolated from raw material by dilute acid extraction, ballast alginates were removed by CaCl2 precipitation, and crude extract was purified by chromatography on DEAE–cellulose. Structure and composition of the fucoidan was characterised by various methods (organic elemental analysis, HPLC analysis of neutral sugars, FTIR, FT-Raman, 1H and 13C NMR); molecular size and charge density were estimated by GPC and CITP. The Miyeokgui fucoidan showed antitumour activity against PC-3 (prostate cancer), HeLa (cervical cancer), A549 (alveolar carcinoma), and HepG2 (hepatocellular carcinoma) cells. Pracoviště Ústav organické chemie a biochemie Kontakt asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434 Rok sběru 2011
Počet záznamů: 1