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Do we need new antibiotics? The search for new targets and new compounds
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SYSNO ASEP 0351521 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Do we need new antibiotics? The search for new targets and new compounds Tvůrce(i) Spížek, Jaroslav (MBU-M)
Novotná, Jitka (MBU-M)
Řezanka, Tomáš (MBU-M) ORCID
Demain, L. A. (US)Zdroj.dok. Journal of Industrial Microbiology & Biotechnology - ISSN 1367-5435
Roč. 37, č. 12 (2010), s. 1241-1248Poč.str. 8 s. Jazyk dok. eng - angličtina Země vyd. DE - Německo Klíč. slova Antibiotics ; Infectious diseases ; Antibiotic resistance Vědní obor RIV EE - Mikrobiologie, virologie CEZ AV0Z50200510 - MBU-M (2005-2011) UT WOS 000284373300005 DOI 10.1007/s10295-010-0849-8 Anotace Resistance to antibiotics and other antimicrobial compounds continues to increase. There are several possibilities for protection against pathogenic microorganisms, for instance, preparation of new vaccines against resistant bacterial strains, use of specific bacteriophages, and searching for new antibiotics. The antibiotic search includes: (1) looking for new antibiotics from nontraditional or less traditional sources, (2) sequencing microbial genomes with the aim of finding genes specifying biosynthesis of antibiotics, (3) analyzing DNA from the environment (metagenomics), (4) reexamining forgotten natural compounds and products of their transformations, and (5) investigating new antibiotic targets in pathogenic bacteria Pracoviště Mikrobiologický ústav Kontakt Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Rok sběru 2011
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