Počet záznamů: 1
Factors enhancing L-valine production by the growth-limited L-isoleucine auxotrophic strain Corynebacterium glutamicum D-eltailvA D-panB ilvNM13 (pECKAilvBNC)
- 1.
SYSNO ASEP 0348125 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Factors enhancing L-valine production by the growth-limited L-isoleucine auxotrophic strain Corynebacterium glutamicum D-eltailvA D-panB ilvNM13 (pECKAilvBNC) Tvůrce(i) Denina, I. (LT)
Paegle, L. (LT)
Prouza, Marek (MBU-M)
Holátko, Jiří (MBU-M)
Pátek, Miroslav (MBU-M) RID, ORCID
Nešvera, Jan (MBU-M) RID
Ruklisha, M. (LT)Zdroj.dok. Journal of Industrial Microbiology & Biotechnology - ISSN 1367-5435
Roč. 37, č. 7 (2010), s. 689-699Poč.str. 11 s. Jazyk dok. eng - angličtina Země vyd. DE - Německo Klíč. slova Corynebacterium glutamicum ; L-valine synthesis ; Limited growth Vědní obor RIV EE - Mikrobiologie, virologie CEP GC204/07/J012 GA ČR - Grantová agentura ČR CEZ AV0Z50200510 - MBU-M (2005-2011) UT WOS 000278835500005 DOI 10.1007/s10295-010-0712-y Anotace The influence of stringent response on production of valine in recombinant strain of Corynebacterium glutamicum was tested. Increased production of valine was most probably caused by high activity of acetohydroxy acid synthase, the key enzyme of the biosynthesis of branched-chain amino acids. Positive effect of stringent response was shown in stationary growth phase due to maintaining high activity of acetohydroxy acid synthase and other enzymes of branched-chain amino acid biosynthesis Pracoviště Mikrobiologický ústav Kontakt Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Rok sběru 2011
Počet záznamů: 1