Počet záznamů: 1
Distribution of polyethylene wear particles and bone fragments in periprosthetic tissue around total hip joint replacements
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SYSNO ASEP 0347024 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Distribution of polyethylene wear particles and bone fragments in periprosthetic tissue around total hip joint replacements Tvůrce(i) Zolotarevova, E. (CZ)
Entlicher, G. (CZ)
Pavlova, Ewa (UMCH-V) RID
Šlouf, Miroslav (UMCH-V) RID, ORCID
Pokorný, D. (CZ)
Veselý, F. (CZ)
Gallo, J. (CZ)
Sosna, A. (CZ)Zdroj.dok. Acta Biomaterialia. - : Elsevier - ISSN 1742-7061
Roč. 6, č. 9 (2010), s. 3595-3600Poč.str. 6 s. Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova joint replacement ; polyethylene ; wear particles distribution Vědní obor RIV CD - Makromolekulární chemie CEP 2B06096 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy CEZ AV0Z40500505 - UMCH-V (2005-2011) UT WOS 000281318400026 DOI 10.1016/j.actbio.2010.04.010 Anotace Ultra-high molecular weight polyethylene (UHMWPE) wear particles play a significant role in failures of total joint replacements (TJRs). In this work, we investigated the distribution of these wear particles in periprosthetic tissues obtained from nine revisions of hip TJR. All periprosthetic tissues were combined and mechanically separated into granuloma tissue (containing hard granules visible to the naked eye) and surrounding tissue (without visible granules). Of the total amount of polyethylene particles in the whole granuloma tissue, 72% of particles in the size range 0.1–10 um and 68% of those larger than 10 um were found in granules. Therefore, the formation of granules significantly lowers the effective amount of wear particles available for interaction with reactive cells and seems to be a natural defense mechanism. Pracoviště Ústav makromolekulární chemie Kontakt Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358 Rok sběru 2011
Počet záznamů: 1