Počet záznamů: 1
Proinflammatory Status, Genetics and Atherosclerosis
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SYSNO ASEP 0343802 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Proinflammatory Status, Genetics and Atherosclerosis Tvůrce(i) Poledne, R. (CZ)
Lorenzová, A. (CZ)
Stávek, P. (CZ)
Valenta, Zdeněk (UIVT-O) RID, SAI, ORCID
Hubáček, J. (CZ)
Suchánek, R. (CZ)
Piťha, J. (CZ)Zdroj.dok. Physiological Research. - : Fyziologický ústav AV ČR, v. v. i. - ISSN 0862-8408
Roč. 58, Suppl. 2 (2009), S111-S118Poč.str. 8 s. Jazyk dok. eng - angličtina Země vyd. CZ - Česká republika Klíč. slova atherosclerosis ; inflammation ; C-reactive protein ; genetics Vědní obor RIV EB - Genetika a molekulární biologie CEP 1M06014 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy CEZ AV0Z10300504 - UIVT-O (2005-2011) UT WOS 000273537200012 EID SCOPUS 77949516701 DOI 10.33549/physiolres.931915 Anotace C-reactive protein concentration analyzed by high sensitivity method (hsCRP) represents a known marker of premature atherosclerosis. Higher concentrations represent an increased individual risk of myocardial infarction and stroke. In a representative sample of the Czech population, a positive relation of hsCRP to BMI, a waist circumference and triglyceride concentration was documented. Substantial sex differences were found in its relationship to age. Whereas it is continuously increasing in men, this increase appears in women only after menopause. A substantial decrease of body weight and visceral fat volume by increased physical activity is accompanied by significant decrease of hsCRP in young obese women. We hypothesized that an increased concentration of hsCRP represents a certain marker of proinflammatory status related to central obesity and triglyceride metabolism and it might be related to individual properties of monocytes in atherogenesis Pracoviště Ústav informatiky Kontakt Tereza Šírová, sirova@cs.cas.cz, Tel.: 266 053 800 Rok sběru 2011
Počet záznamů: 1