Počet záznamů: 1

New defensins from hard and soft ticks: Similarities, differences, and phylogenetic analyses

SYSNO ASEP	0342882
Druh ASEP	J - Článek v odborném periodiku
Zařazení RIV	J - Článek v odborném periodiku
Poddruh J	Článek ve WOS
Název	New defensins from hard and soft ticks: Similarities, differences, and phylogenetic analyses
Tvůrce(i)	Chrudimská, Tereza (BC-A) Chrudimský, Tomáš (BC-A)_RID Golovchenko, Maryna (BC-A)_{RID, ORCID} Rudenko, Natalia (BC-A)_{RID, ORCID} Grubhoffer, Libor (BC-A)_{RID, ORCID}
Zdroj.dok.	Veterinary Parasitology. - : Elsevier - ISSN 0304-4017 Roč. 167, 2/4 (2010), s. 298-303
Poč.str.	6 s.
Jazyk dok.	eng - angličtina
Země vyd.	NL - Nizozemsko
Klíč. slova	innate immunity ; Ixodidae ; Argasidae ; defensin
Vědní obor RIV	EB - Genetika a molekulární biologie
CEP	GA524/06/1479 GA ČR - Grantová agentura ČR
	GD206/09/H026 GA ČR - Grantová agentura ČR
	LC06009 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy
CEZ	AV0Z60220518 - PAU-O, BC-A (2005-2011)
UT WOS	000274942600023
DOI	10.1016/j.vetpar.2009.09.032
Anotace	Despite the importance of ticks as vectors of disease very little is known about their immune system. Antimicrobial peptides, including defensins (phylogenetically ancient antibacterial peptides) are major components of innate immunity in ticks that have been shown to provide protection against gram-negative and gram-positive bacteria, fungi, viruses and protozoan parasites. With the aim of studying the evolution of the genes involved in tick defense, we identified the preprodefensin genes from four Ornithodoros tick species (O. papillipes: isoforms A, B, and D; O. tartakovskyi and O. puertoricensis: isoforms A and B; O. rostratus: isoform A) and from two Dermacentor tick species (D. reticulatus and D. marginatus: one isoform) not previously described. Phylogenetic analyses revealed that Ornithodoros defensin isoforms (A, B, C, and D) form 4 separate clades, while hard tick defensins are divided into several branches based on particular tick species.
Pracoviště	Biologické centrum (od r. 2006)
Kontakt	Dana Hypšová, eje@eje.cz, Tel.: 387 775 214
Rok sběru	2011

Počet záznamů: 1