Počet záznamů: 1
IRESite - a Tool for The Examination of Viral and Cellular Internal Ribosome Entry Sites
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SYSNO ASEP 0340720 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název IRESite - a Tool for The Examination of Viral and Cellular Internal Ribosome Entry Sites Tvůrce(i) Mokrejš, M. (CZ)
Mašek, T. (CZ)
Vopálenský, V. (CZ)
Hlubuček, P. (CZ)
Delbos, P. (CZ)
Pospíšek, Martin (UIVT-O)Zdroj.dok. Nucleic Acids Research. - : Oxford University Press - ISSN 0305-1048
Roč. 38, DB Issue (2010), D131-D136Poč.str. 6 s. Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova IRESite ; IRES ; translation ; virus ; database Vědní obor RIV EB - Genetika a molekulární biologie CEP 1M06014 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy UT WOS 000276399100021 EID SCOPUS 75549090211 DOI 10.1093/nar/gkp981 Anotace The IRESite presents curated experimental evidence of many eukaryotic viral and cellular internal ribosome entry site (IRES) regions. The IRESite stores > 600 records and gradually evolved into a robust tool providing (i) biologically meaningful information regarding the IRESs and their experimental background as well as (ii) thorough concluding remarks to stored database entries and regularly updated evaluation of the reported IRES function. A substantial portion of the IRESite data results purely from in-house bioinformatic analyses of currently available sequences, in silico attempts to repeat published cloning experiments, DNA sequencing and restriction endonuclease verification of received plasmid DNA. IRESite contains a newly implemented tool for displaying RNA secondary structures and for searching through the structures currently stored in the database. The supplementary material contains an updated list of reported IRESs. Pracoviště Ústav informatiky Kontakt Tereza Šírová, sirova@cs.cas.cz, Tel.: 266 053 800 Rok sběru 2010
Počet záznamů: 1