Počet záznamů: 1
Mitochondria and Cancer
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SYSNO ASEP 0340634 Druh ASEP M - Kapitola v monografii Zařazení RIV C - Kapitola v knize Název Mitochondria as targets for cancer therapy Tvůrce(i) Ralph, S. J. (AU)
Neužil, Jiří (BTO-N) RIDZdroj.dok. Mitochondria and Cancer. - New York : Springer Science + Business Media, 2009 - ISBN 978-0-387-84834-1 Rozsah stran s. 211-249 Poč.str. 39 s. Poč.výt. 500 Poč.str.knihy 291 Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova Cancer cell mitochondria ; reactive oxygen species ; anti-cancer drugs Vědní obor RIV FD - Onkologie a hematologie CEZ AV0Z50520701 - BTO-N (2007-2013) Anotace Many recent literature findings illustrate the fact that a variety of compounds active in cancer cells act via mitochondria. These compounds, termed mitocans, destabilise mitochondria and cause apoptosis, which is, at least in some cases, selective for cancer cells. Thus, novel drugs offer substantial promise as potent and effective clinical treatments with minimal side-effects. The chapter on mitochondria as targets for cancer therapy is included in the book presenting thorough analyses of mitochondrial dysfunction as one of the hallmarks of cancer and discussing the clinical implications of cancer mitochondrial defects Pracoviště Biotechnologický ústav Kontakt Monika Kopřivová, Monika.Koprivova@ibt.cas.cz, Tel.: 325 873 700 Rok sběru 2010
Počet záznamů: 1