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Comparison of in vitro tests for measurement of estrogenity of chlorinated compounds and their use in the evaluation of biodegradation of chlorbenzoates by the fungus Panus tigrinus
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SYSNO ASEP 0339618 Druh ASEP C - Konferenční příspěvek (mezinárodní konf.) Zařazení RIV D - Článek ve sborníku Název Comparison of in vitro tests for measurement of estrogenity of chlorinated compounds and their use in the evaluation of biodegradation of chlorbenzoates by the fungus Panus tigrinus Tvůrce(i) Svobodová, Kateřina (MBU-M) RID
Covino, S. (IT)
Křesinová, Zdena (MBU-M) RID
Cajthaml, Tomáš (MBU-M) RID, ORCIDZdroj.dok. Odpadové fórum 2009 - sborník přednášek. - Praha : PCHE-PetroChemEng, 2009 - ISBN 978-80-02-02108-7 Rozsah stran s. 3619-3623 Poč.str. 5 s. Akce Odpadové fórum Datum konání 22.04.2009-24.04.2009 Místo konání Milovy Země CZ - Česká republika Typ akce EUR Jazyk dok. eng - angličtina Země vyd. CZ - Česká republika Klíč. slova yeast assay ; biodegradation ; chlorbenzoates Vědní obor RIV EE - Mikrobiologie, virologie CEP 2B06156 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy CEZ AV0Z50200510 - MBU-M (2005-2011) Anotace Recently, contamination of the environment by endocrine disruptive compounds, toxicity of these chemicals and their biodegradability are widely studied. This work is focused on estrogenity of chlorinated phenols and chlorbenzoic acids that represent potential degradation products of PCB compounds. Two different yeast bioassays for evaluation of estrogenity based on recombinated strains of Saccharomyces cerevisie were compared in this work. Estrogenic activity of chlorbenzoic acids varied with the chemical structure of chemicals. A mixture of chlorbenzoates (initial concentration 10 ppm) was degraded by a ligninolytic fungus Panus tigrinus in liquid cultures. Chemicals resulting from degradation were tested for their estrogenity, however, results indicated that the test responses were inhibited probably by some compounds present in the fungal culture liquid Pracoviště Mikrobiologický ústav Kontakt Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Rok sběru 2010
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