Počet záznamů: 1
Negative relationships between cellular immune response, Mhc class II heterozygosity and secondary sexual trait in the montane water vole
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SYSNO ASEP 0337712 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Negative relationships between cellular immune response, Mhc class II heterozygosity and secondary sexual trait in the montane water vole Tvůrce(i) Charbonnel, N. (FR)
Bryja, Josef (UBO-W) RID, SAI, ORCID
Galan, M. (FR)
Deter, J. (FR)
Tollenaere, C. (FR)
Chaval, Y. (FR)
Morand, S. (FR)
Cosson, J.-F. (FR)Celkový počet autorů 8 Zdroj.dok. Evolutionary Applications. - : Wiley - ISSN 1752-4571
Roč. 3, č. 3 (2010), s. 279-290Poč.str. 12 s. Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova abundance cycles ; Dqa and Drb ; immunocompetence handicap ; Mhc class II genes ; parasite-mediated balancing selection ; sexual selection Vědní obor RIV EB - Genetika a molekulární biologie CEZ AV0Z60930519 - UBO-W (2005-2011) UT WOS 000276790700004 EID SCOPUS 77954309014 DOI 10.1111/j.1752-4571.2009.00108.x Anotace Heterogeneities in immune responsiveness may affect key epidemiological parameters and the dynamics of pathogens. We analysed the influence of Major histocompatibility complex (Mhc) genes and epigamic traits on the response to phytohaemagglutinin in males from cyclic populations of the montane water vole (Arvicola scherman). We found a negative relationship between Mhc hetetozygosity and response to phytohaemagglutinin, mediated by a specific Mhc genotype (Arte-Dqa-05 homozygous genotype being a ‘good’ Mhc variant in terms of immunogenetic quality). The development of the scent glands seems to be an honest signal for mate choice as it is negatively correlated with helminth load. The ‘good gene’ hypothesis was not validated as Arte-Dqa-05 homozygous males did not exhibit larger glands. Besides, the negative relationship observed between the size of these glands and the response to phytohaemagglutinin, mainly for Mhc homozygotes, corroborates the immunocompetence handicap hypothesis. Pracoviště Ústav biologie obratlovců Kontakt Hana Slabáková, slabakova@ivb.cz, Tel.: 543 422 524 Rok sběru 2011
Počet záznamů: 1