Počet záznamů: 1

Effect of polychlorinated biphenyls (PCBs) and 1,1,1-trichloro-2,2,-bis (4-chlorophenyl)-ethane (DDT) in follicular fluid on the results of in vitro fertilization-embryo transfer (IVF-ET) programs

SYSNO ASEP	0337397
Druh ASEP	J - Článek v odborném periodiku
Zařazení RIV	J - Článek v odborném periodiku
Poddruh J	Článek ve WOS
Název	Effect of polychlorinated biphenyls (PCBs) and 1,1,1-trichloro-2,2,-bis (4-chlorophenyl)-ethane (DDT) in follicular fluid on the results of in vitro fertilization-embryo transfer (IVF-ET) programs
Tvůrce(i)	Jirsová, S. (CZ) Mašata, J. (CZ) Jech, L. (CZ) Zvárová, Jana (UIVT-O)_{SAI, RID, ORCID}
Zdroj.dok.	Fertility and Sterility. - : Elsevier - ISSN 0015-0282 Roč. 93, č. 6 (2010), s. 1831-1836
Poč.str.	6 s.
Jazyk dok.	eng - angličtina
Země vyd.	US - Spojené státy americké
Klíč. slova	DDD ; DDE ; DDT ; embryos ; oocytes ; PCB ; pregnancy rate
Vědní obor RIV	FK - Gynekologie a porodnictví
CEZ	AV0Z10300504 - UIVT-O (2005-2011)
UT WOS	000276678100015
EID SCOPUS	77950300713
DOI	10.1016/j.fertnstert.2008.12.063
Anotace	We analyzed the influence of polychlorinated biphenyls (PCBs) and pesticides in follicular fluid on the number of fertilized oocytes, the quality of oocytes and embryos, pregnancy rate, and number of embryos cryoconserved in IVF-ET program. We collected the follicular fluid of 99 infertile women. The PCB levels varied from 0.1 to 254.6 ng/g of fat. Levels of DDT and its metabolites varied from 0.3 to 35 228.8 ng/g of fat. A correlation was found between the number of diploid oocytes and the level of DDT, the fertilization of oocytes and level of PCB 158, and the pregnancy rate and the number of embryos cryoconserved and levels of PCB 47. Xenobiotics can be detected in the fat compartment of the follicular fluid. Some correlation to the IVF-ET program results was established, to a degree that might be considered of concern, although it was not statistically significant at the 5% level.
Pracoviště	Ústav informatiky
Kontakt	Tereza Šírová, sirova@cs.cas.cz, Tel.: 266 053 800
Rok sběru	2011

Počet záznamů: 1