Petrovová, E. (SK) Sedmera, David (UZFG-Y) Míšek, Ivan (UZFG-Y) Lešník, František (UZFG-Y) Luptáková, L. (SK)
Zdroj.dok.
Folia Biologica. - : Univerzita Karlova v Praze
- ISSN 0015-5500
Roč. 55, č. 1 (2009), s. 61-65
Poč.str.
5 s.
Jazyk dok.
eng - angličtina
Země vyd.
CZ - Česká republika
Klíč. slova
carbamate ; pesticides ; embryotoxicity
Vědní obor RIV
EA - Morfologické obory a cytologie
CEZ
AV0Z50450515 - UZFG-Y (2005-2011)
Anotace
Embryotixicity of choline esterase inhibitor bendiocarbamate was studied in the chick embryo. The pesticide was dissolved in 5% aceton in distilled water and volume of 200 microliters was administered over the embryo through membrana papyracea at embryonic days (ED) 2, 3, 4, 5, and 10. Sampling was performed on ED 10, while the embryos treated on ED 10 were sampled on ED 17. The toxicity of bendiocarbamete was fairly low, and LD50 decreased with advancing development from 1 mg/embryo at ED 2 to 29 mg on ED 5.In embryos treated on ED 3 and 4 and examined with supravital whole mount staining with Lysotracker Red for apoptosis was observed a mild increase in number of positive cells in the eye, limb buds, and the central nervous system. In agreement with previously published studies in other vertebrate animals, we conclude that bendiocarbamate does not possess significant toxicity in the avian embryo.
Pracoviště
Ústav živočišné fyziologie a genetiky
Kontakt
Jana Zásmětová, knihovna@iapg.cas.cz, Tel.: 315 639 554
Rok sběru
2009
Počet záznamů: 1
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