Počet záznamů: 1  

Variability of Phase Shift Between Blood Pressure and Heart Rate Fluctuations - A Marker of Short-Term Circulation Control

  1. 1.
    SYSNO ASEP0205681
    Druh ASEPJ - Článek v odborném periodiku
    Zařazení RIVJ - Článek v odborném periodiku
    Poddruh JOstatní články
    NázevVariability of Phase Shift Between Blood Pressure and Heart Rate Fluctuations - A Marker of Short-Term Circulation Control
    Tvůrce(i) Halámek, Josef (UPT-D) RID, ORCID, SAI
    Kára, T. (CZ)
    Jurák, Pavel (UPT-D) RID, ORCID, SAI
    Souček, M. (CZ)
    Francis, D. (GB)
    Davies, L. C. (GB)
    Shen, W. K. (US)
    Coats, A. J. (GB)
    Novák, M. (CZ)
    Nováková, Z. (CZ)
    Panovský, R. (CZ)
    Toman, J. (CZ)
    Šumbera, J. (CZ)
    Somers, V. K. (US)
    Zdroj.dok.Circulation - ISSN 0009-7322
    Roč. 108, č. 3 (2003), s. 292 - 297
    Poč.str.6 s.
    Jazyk dok.eng - angličtina
    Země vyd.US - Spojené státy americké
    Klíč. slovabaroreceptors ; respiration ; sudden death
    Vědní obor RIVFA - Kardiovaskulární nemoci vč. kardiochirurgie
    CEPGA102/00/1262 GA ČR - Grantová agentura ČR
    GA102/02/1339 GA ČR - Grantová agentura ČR
    CEZAV0Z2065902 - UPT-D
    AnotaceBackground - We postulated that the variability of the phase shift between blood pressure and heart rate fluctuation near the frequency of 0.10 Hz might be useful in assessing autonomic circulatory control. Methods and Results - We tested this hypothesis in 4 groups of subjects: 28 young, healthy individuals; 13 elderly healthy individuals; patients with coronary heart disease; and 19 patients with a planned or implanted cardioverter-defibrillator (ICD recipients). Data from 5 minutes of free breathing and at 2 different, controlled breathing frequencies (0.10 and 0.33 Hz) were used. Clear differences (P<0.001) in variability of phase were evident between the ICD recipients and all other groups. Furthermore, at a breathing frequency of 0.10 Hz, differences in baroreflex sensitivity (P<0.01) also became evident, even though these differences were not apparent at the 0.33-Hz breathing frequency. Conclusions - The frequency of 0.01 Hz represents a useful and potentially important one for controlled breathing, at which differences in blood pressure - RR interactions become evident. These interactions, whether computed as a variability of phase to define stability of the blood pressure-heart rate interaction or defined as the baroreflex sensitivity to define the gain in heart rate response to blood pressure changes, are significantly different in patients at risk for sudden arrhythmic death. In young versus older healthy individuals, only baroreflex gain is different, with the variability of phase being similar in both groups. The measurements of short-term circulatory control might help in risk stratification for sudden cardiac death.
    PracovištěÚstav přístrojové techniky
    KontaktMartina Šillerová, sillerova@ISIBrno.Cz, Tel.: 541 514 178
    Rok sběru2004

Počet záznamů: 1  

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