A correctly chosen cover offers the optimal means for a fast re-epithelization of wounds (burns, donor sites, leg ulcers and other skin deffect). There has been a positive experience with primary covering of burn wounds with surwiwing porcine dermo-epidermal grafts (xenografts) in the Prague Burn Centre of the Charles University Hospital for more than three decades. lThe siccessfull clinical practice led us to develop the dried porcine dermal matrix, which was further improved and commercialized as the BioSkin s.r.o.