Folia Biologica. - : Univerzita Karlova v Praze
- ISSN 0015-5500
Roč. 50, 3-4 (2004), s. 120-130
Poč.str.
11 s.
Jazyk dok.
eng - angličtina
Země vyd.
CZ - Česká republika
Klíč. slova
interleukin 2 ; cancer therapy
Vědní obor RIV
EC - Imunologie
CEP
NC7148 GA MZd - Ministerstvo zdravotnictví
GA301/04/0492 GA ČR - Grantová agentura ČR
IAA5052203 GA AV ČR - Akademie věd
CEZ
AV0Z5052915 - UMG-J
Anotace
The aim of this review was to evaluate the results of IL-2 therapy of cancer two decades after the first experiments and to discuss whether and which results of local, systemic and adjuvant IL-2 therapy in preclinical models can be translated into clinics. The attention was also focused on the development and utilization of the IL-2 gene-modified tumour vaccines for therapeutic purposes. The prospects and limitations of both, IL-2 therapy and IL-2 gene therapy were discussed
