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Antioxidant Vitamin Levels Do Not Exhibit Negative Correlation with the Extent of Acute Myocardial Infarction
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SYSNO ASEP 0030943 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Ostatní články Název Antioxidant Vitamin Levels Do Not Exhibit Negative Correlation with the Extent of Acute Myocardial Infarction Překlad názvu Hladiny antioxidačních vitamínů nevykazují negativní korelaci s rozsahem akutního infarktu myokardu Tvůrce(i) Mužáková, V. (CZ)
Vojtíšek, P. (CZ)
Meloun, M. (CZ)
Vaňková, Radomíra (UEB-Q) RID, ORCID
Toušar, T. (CZ)
Červinková, Z. (CZ)Zdroj.dok. Physiological Research. - : Fyziologický ústav AV ČR, v. v. i. - ISSN 0862-8408
Roč. 54, č. 6 (2005), s. 623-629Poč.str. 7 s. Jazyk dok. eng - angličtina Země vyd. CZ - Česká republika Klíč. slova Antioxidant vitamins ; α-Tocopherol ; β-Carotene Vědní obor RIV ED - Fyziologie CEZ AV0Z50380511 - UEB-Q (2005-2011) 021627502 Anotace Serum levels of vitamin E (VE), β-carotene (BC) and vitamin C (VC) were determined in 50 patients with the first acute myocardial infarction (AMI) before starting thrombolytical treatment. VE and BC were determined by HPLC, VC spectrophotometrically. The reperfused patients were divided according to vitamin concentrations into four groups. The lowest quartile was compared with the rest of the studied population (VE: group with high (H) > 15.6 μM > group with low (L), BC: H > 0.07 μM > L, VC: H > 25 μM > L) in the following parameters: extent of myocardial damage (area under the curves of troponin I, CK-MB during 48 h), arrhythmia and congestive heart failure occurrence, size of ejection fraction, positivity of ventricular late potentials. No significant differences between groups H and L for either VE, BC or VC were found (P±0.05). As no correlation between serum concentrations of vitamins E, C and β-carotene and the extent and clinical course of AMI was found, the actual vitamin concentrations may be important for prevention of ischemic heart a disease, but they do not play a decisive role in the acute phase of myocardial infarction in humans. Pracoviště Ústav experimentální botaniky Kontakt David Klier, knihovna@ueb.cas.cz, Tel.: 220 390 469 Rok sběru 2006
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