An enigmatic catalase of Blastocrithidia

0520657 - BC 2020 RIV NL eng J - Článek v odborném periodiku
Bianchi, C. - Kostygov, A.Y. - Kraeva, N. - Záhonová, Kristýna - Horáková, Eva - Sobotka, Roman - Lukeš, Julius - Yurchenko, Vyacheslav
An enigmatic catalase of Blastocrithidia.
Molecular and Biochemical Parasitology. Roč. 232, SEP 2019 (2019), č. článku 111199. ISSN 0166-6851. E-ISSN 1872-9428
Grant CEP: GA MŠMT(CZ) LL1601; GA MŠMT(CZ) EF16_019/0000759
Institucionální podpora: RVO:60077344 ; RVO:61388971
Klíčová slova: evolution * Oxygen peroxide * Catalase * Trypanosomatidae
Obor OECD: Genetics and heredity (medical genetics to be 3); Biochemistry and molecular biology (MBU-M)
Impakt faktor: 1.571, rok: 2019
Způsob publikování: Omezený přístup
https://www.sciencedirect.com/science/article/pii/S0166685119300684

Here we report that trypanosomatid flagellates of the genus Blastocrithidia possess catalase. This enzyme is not phylogenetically related to the previously characterized catalases in other monoxenous trypanosomatids, suggesting that their genes have been acquired independently. Surprisingly, Blastocrithidia catalase is less enzymatically active, compared to its counterpart from Leptomonas pyrrhocoris, posing an intriguing biological question why this gene has been retained in the evolution of trypanosomatids.
Trvalý link: http://hdl.handle.net/11104/0305298