Structural Basis of the Interaction of Cyclin-Dependent Kinase 2 with Roscovitine and Its Analogues Having Bioisosteric Central Heterocycles

0476134 - ÚOCHB 2018 RIV DE eng J - Článek v odborném periodiku
Nekardová, Michaela - Vymětalová, Ladislava - Khirsariya, P. - Kováčová, S. - Hylsová, M. - Jorda, Radek - Kryštof, Vladimír - Fanfrlík, Jindřich - Hobza, Pavel - Paruch, K.
Structural Basis of the Interaction of Cyclin-Dependent Kinase 2 with Roscovitine and Its Analogues Having Bioisosteric Central Heterocycles.
ChemPhysChem. Roč. 18, č. 7 (2017), s. 785-795. ISSN 1439-4235. E-ISSN 1439-7641
Grant CEP: GA ČR(CZ) GBP208/12/G016; GA ČR(CZ) GA15-15264S
Institucionální podpora: RVO:61388963 ; RVO:61389030
Klíčová slova: computational chemistry * enzymes * protein-inhibitor interactions * purine bioisosteres * scaffold hopping
Obor OECD: Physical chemistry
Impakt faktor: 2.947, rok: 2017
Trvalý link: http://hdl.handle.net/11104/0272666