Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells

BAJZIKOVÁ, Martina, KOVÁŘOVÁ, Jaromíra, COELHO, Ana R., BOUKALOVÁ, Štěpána, OH, S., ROHLENOVÁ, Kateřina, ŠVEC, David, HUBÁČKOVÁ, Soňa, ENDAYA, B., JUDASOVÁ, Kateřina, BEZAWORK-GELETA, A., KLUČKOVÁ, Katarína, CHATRE, L., ZOBALOVÁ, Renata, NOVÁKOVÁ, Anna, VÁŇOVÁ, Kateřina, EZROVÁ, Zuzana, MAGHZAL, G. J., NOVAIS, Silvia Magalhaes, OLSINOVA, M., KROBOVÁ, Linda, AN, Y. J., DAVIDOVÁ, Eliška, NAHÁCKA, Zuzana, SOBOL, Margaryta, CUNHA-OLIVEIRA, T., SANDOVAL-ACUNA, Cristian, STRNAD, Hynek, ZHANG, T., HUYNH, T., SERAFIM, T. L., HOZÁK, Pavel, SARDAO, V. A., KOOPMAN, W. J. H., RICCHETTI, M., OLIVEIRA, P. J., KOLÁŘ, František, KUBISTA, Mikael, TRUKSA, Jaroslav, DVOŘÁKOVÁ-HORTOVÁ, Kateřina, PACAK, K., GÜRLICH, R., STOCKER, R., ZHOU, Y., BERRIDGE, M.V., PARK, S., DONG, L., ROHLENA, Jakub, NEUŽIL, Jiří. Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells. Cell Metabolism. 2019, 29(2), 399-416. ISSN 1550-4131. E-ISSN 1932-7420. Dostupné z: doi: 10.1016/j.cmet.2018.10.014.