Počet záznamů: 1
Distinct effects of Sonic hedgehog and Wnt-7a on differentiation of neonatal neural stem/progenitor cells in vitro
- 1.0349062 - ÚEM 2011 RIV GB eng J - Článek v odborném periodiku
Prajerová, Iva - Honsa, Pavel - Chvátal, Alexandr - Anděrová, Miroslava
Distinct effects of Sonic hedgehog and Wnt-7a on differentiation of neonatal neural stem/progenitor cells in vitro.
Neuroscience. Roč. 171, č. 3 (2010), s. 693-711. ISSN 0306-4522. E-ISSN 1873-7544
Grant CEP: GA ČR GA305/09/0717; GA MŠMT(CZ) LC554
Grant ostatní: GA ČR(CZ) GD309/08/H079; GA MŠk(CZ) 1M0538
Program: 1M
Výzkumný záměr: CEZ:AV0Z50390512
Klíčová slova: morphogen * potassium currents * sodium currents
Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
Impakt faktor: 3.215, rok: 2010
http://arl-repository.lib.cas.cz/uloziste_av/UEM-P/cav_un_epca-0349062_01.pdf
We explored the effect of two morphogens Sonic hedgehog and Wnt-7a on the proliferation, differentiation and membrane properties of neonatal neural stem/progenitor cells (NS/PCs) transduced with either Shh- or Wnt-7a. We found that Shh and Wnt-7a interfere differently with the process of neuronal differentiation and that they promote electrophysiologically and immunohistochemically distinct stages of neuronal differentiation in neonatal NS/PCs.
Trvalý link: http://hdl.handle.net/11104/0189399
Počet záznamů: 1