Počet záznamů: 1
Alternative synthesis of 9-{3-[(diisopropoxyphosphoryl)-methoxy]-2-hydroxypropyl}adenine and its free phosphonates substituted at the C-8 position of purine base
- 1.0343322 - ÚOCHB 2011 RIV CZ eng J - Článek v odborném periodiku
Janeba, Zlatko - Masojídková, Milena - Holý, Antonín
Alternative synthesis of 9-{3-[(diisopropoxyphosphoryl)-methoxy]-2-hydroxypropyl}adenine and its free phosphonates substituted at the C-8 position of purine base.
Collection of Czechoslovak Chemical Communications. Roč. 75, č. 3 (2010), s. 371-381. ISSN 0010-0765
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: acyclic nucleoside phosphonates * HPMPA * nucleophilic substitution * intramolecular cyclization
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 0.853, rok: 2010
New approach to 9-[2-hydroxy-3-(phosphonomethoxy)propyl]adenine (iso-HPMPA) is described and a series of iso-HPMPA derivatives substituted at the C-8 position of the purine ring was prepared. Synthesis of the key alkylating agent was developed starting from allyl alcohol.
Trvalý link: http://hdl.handle.net/11104/0185828
Počet záznamů: 1