Počet záznamů: 1
Morphological changes in human neural cells followign tick-borne encephalitis infection
- 1.0335287 - BC 2010 RIV GB eng J - Článek v odborném periodiku
Růžek, Daniel - Vancová, Marie - Tesařová, Martina - Ahantarig, A. - Kopecký, Jan - Grubhoffer, Libor
Morphological changes in human neural cells followign tick-borne encephalitis infection.
Journal of General Virology. Roč. 90, č. 7 (2009), s. 1649-1658. ISSN 0022-1317. E-ISSN 1465-2099
Grant CEP: GA ČR GA524/08/1509; GA MŠMT(CZ) LC06009
Výzkumný záměr: CEZ:AV0Z60220518
Klíčová slova: tick-borne encephalitis virus * human neural cells * central nervous system
Kód oboru RIV: EE - Mikrobiologie, virologie
Impakt faktor: 3.260, rok: 2009
Tick-borne encephalitis (TBE) is one of the leading and most dangerous human viral neuroinfections in Europe and north-eastern Asia. The clinical manifestations include asymptomatic infections, fevers and debilitating encephalitis that might progress into chronic disease or fatal infection. To understand TBE pathology further in host nervous systems, three human neural cell lines, neuroblastoma, medulloblastoma and glioblastoma, were infected with TBE virus (TBEV). The susceptibility and virus-mediated cytopathic effect, including ultrastructural and apoptotic changes of the cells, were examined. The neuropathological significance of the observations is discussed.
Trvalý link: http://hdl.handle.net/11104/0179794
Počet záznamů: 1